Results 61 to 70 of about 126,855 (275)

Unexpected complexity of everyday manual behaviors

Nature Communications, 2020
How does the brain control the complex movements of hands? Here, by tracking human hand kinematics and applying multidimensional reduction techniques, the authors provide evidence that grasping involves a complex control system that regulates even the ...
Yuke Yan, James M. Goodman, Dalton D. Moore, Sara A. Solla, Sliman J. Bensmaia   +4 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Towards Explainable Deep Learning in Computational Neuroscience: Visual and Clinical Applications

Mathematics
Deep learning has emerged as a powerful tool in computational neuroscience, enabling the modeling of complex neural processes and supporting data-driven insights into brain function. However, the non-transparent nature of many deep learning models limits
Asif Mehmood, Faisal Mehmood, Jungsuk Kim   +2 more
doaj   +1 more source

Decoding the ERD/ERS: influence of afferent input induced by a leg assistive robot

Frontiers in Systems Neuroscience, 2014
This paper investigates the influence of the leg afferent input, induced by a leg assistive robot, on the decoding performance of a BMI system. Specifically, it focuses on a decoder based on the event-related (de)synchronization (ERD/ERS) of the ...
Giuseppe eLisi, Giuseppe eLisi, Tomoyuki eNoda, Jun eMorimoto   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Equilibrium and response properties of the integrate-and-fire neuron in discrete time

Frontiers in Computational Neuroscience, 2010
The integrate-and-fire neuron with exponential postsynaptic potentials is a frequently employed model to study neural networks. Simulations in discrete time still have highest performance at moderate numerical errors, which makes them first choice for ...
Moritz Helias, Moritz Helias, Moritz Deger, Moritz Deger, Markus Diesmann, Markus Diesmann, Markus Diesmann, Stefan Rotter, Stefan Rotter   +8 more
doaj   +1 more source

Automatic Generation of Cognitive Theories using Genetic Programming

, 2007
Cognitive neuroscience is the branch of neuroscience that studies the neural mechanisms underpinning cognition and develops theories explaining them. Within cognitive neuroscience, computational neuroscience focuses on modeling behavior, using theories ...
Frias-Martinez, E, Gobet, F
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

COMPUTATIONAL NEUROSCIENCE FOR ADVANCING ARTIFICIAL INTELLIGENCE

Cuadernos de Neuropsicología, 2011
resumen del libro de Alonso, E. y Mondragón, E. (2011). Hershey, NY: Medical Information Science Reference. La neurociencia como disciplinapersigue el entendimiento del cerebro y su relación con el funcionamiento de la mente a través del análisis de la ...
Fernando P. Ponce
doaj   +2 more sources

Looking for effects of qualia on event-related brain potentials of close others in search for a cause of the similarity of qualia assumed across individuals [version 3; referees: 2 approved]

F1000Research, 2018
Qualia, the individual instances of subjective conscious experience, are private events. However, in everyday life, we assume qualia of others and their perceptual worlds, to be similar to ours.
Sheila Bouten, Hugo Pantecouteau, J. Bruno Debruille   +2 more
doaj   +1 more source