Results 71 to 80 of about 4,141,656 (337)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Frontiers in Materials, 2020 During the past two decades, the high-entropy alloy AlCoCrFeNi has attracted much attention due to its outstanding thermal and mechanical properties under ambient conditions.
Juefei Wu +8 more
doaj +1 more source
Nuclear Fusion, 2023 Based on the kinetic theory, improved T -matrix models for the continuous-slowing-down and the linear-energy-transfer stopping powers are established at the same level, where multiple scattering effects and the related transverse deflection are accounted
Chengliang Lin +3 more
doaj +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Linear analysis of Atwood number effects on shear instability in the elastic–plastic solids
Scientific Reports, 2021 The evolution of shear instability between elastic–plastic solid and ideal fluid which is concerned in oblique impact is studied by developing an approximate linear theoretical model.
Xi Wang +4 more
doaj +1 more source
The benefit of computational modelling in physics teaching: a historical overview
European journal of physics, 2020 Computational modelling is not only an important element in scientific research, it also has a rich history in physics education and its application in the classroom has changed greatly over the last few decades. To explain why computational modelling is
J. Weber, T. Wilhelm
semanticscholar +1 more source
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source
Hydrodynamic Kelvin–Helmholtz instability on metallic surface
Scientific Reports, 2023 Kelvin–Helmholtz instability on metallic surface is relevant to intense oblique impact in many physical processes such as explosive welding, Inertial Confinement Fusion and planetary impact events.
Xi Wang +4 more
doaj +1 more source
Reproducible Experiment Platform
, 2015 Data analysis in fundamental sciences nowadays is an essential process that pushes frontiers of our knowledge and leads to new discoveries. At the same time we can see that complexity of those analyses increases fast due to a)~enormous volumes of ...
Baranov, Alexander +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu +15 more
wiley +1 more source