Results 51 to 60 of about 135,074 (266)

Semantics of Computable Physical Models

Studia Logica, 2023
AbstractThis article reformulates the theory of computable physical models, previously introduced by the author, as a branch of applied model theory in first-order logic. It provides a semantic approach to the philosophy of science that incorporates aspects of operationalism and Popper’s degrees of falsifiability.
openaire   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Hydrodynamic Kelvin–Helmholtz instability on metallic surface

Scientific Reports, 2023
Kelvin–Helmholtz instability on metallic surface is relevant to intense oblique impact in many physical processes such as explosive welding, Inertial Confinement Fusion and planetary impact events.
Xi Wang, Xiao-Mian Hu, Sheng-Tao Wang, Hao Pan, Jian-Wei Yin   +4 more
doaj   +1 more source

Morphological Computation: Nothing but Physical Computation [PDF]

Entropy, 2018
The purpose of this paper is to argue against the claim that morphological computation is substantially different from other kinds of physical computation. I show that some (but not all) purported cases of morphological computation do not count as specifically computational, and that those that do are solely physical computational systems. These latter
openaire   +3 more sources

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

Deep-learning potential method to simulate shear viscosity of liquid aluminum at high temperature and high pressure by molecular dynamics

AIP Advances, 2021
The shear viscosity of matter and efficient simulating methods in a wide range of temperatures and densities are desirable. In this study, we present the deep-learning many-body potential (the deep potential) method to reduce the computational cost of ...
Yuqing Cheng, Han Wang, Shuaichuang Wang, Xingyu Gao, Qiong Li, Jun Fang, Hongzhou Song, Weidong Chu, Gongmu Zhang, Haifeng Song, Haifeng Liu   +10 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Safety and Effectiveness of Triple-Antenna Hepatic Microwave Ablation

Bioengineering
Microwave ablation is becoming a standard procedure for treating tumors based on heat generation, causing an elevation in the tissue temperature level from 50 to 60 °C, causing tissue death.
Nikola Bošković, Srdjan Nikolić, Branislav Radjenović, Marija Radmilović-Radjenović   +3 more
doaj   +1 more source

Quantum algorithms for computational nuclear physics

EPJ Web of Conferences, 2015
While quantum algorithms have been studied as an efficient tool for the stationary state energy determination in the case of molecular quantum systems, no similar study for analogical problems in computational nuclear physics (computation of energy ...
Višňák Jakub
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source