Results 51 to 60 of about 941,372 (293)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Physics computational literacy: Programming, modeling, and collaboration at the journeyman level

open access: yesPhysical Review Physics Education Research
Computation has become an integral part of physics research. However, little is known about how students learn to productively use computation as a tool beyond the introductory level, especially as they transition into physics research. In this study, we
Karl Henrik Fredly   +2 more
doaj   +1 more source

Structural and Thermodynamic Properties of the High-Entropy Alloy AlCoCrFeNi Based on First-Principles Calculations

open access: yesFrontiers in Materials, 2020
During the past two decades, the high-entropy alloy AlCoCrFeNi has attracted much attention due to its outstanding thermal and mechanical properties under ambient conditions.
Juefei Wu   +8 more
doaj   +1 more source

Generation of high intensity speckles in overlapping laser beams

open access: yesMatter and Radiation at Extremes, 2023
A new mechanism for the generation of high intensity speckles by coupling of overlapping beams is discovered and studied in detail. Using three-dimensional simulations, the coupling of overlapping beams smoothed by phase plates and by polarization ...
Liang Hao, Jie Qiu, Wen Yi Huo
doaj   +1 more source

Steering in computational science: mesoscale modelling and simulation

open access: yes, 2003
This paper outlines the benefits of computational steering for high performance computing applications. Lattice-Boltzmann mesoscale fluid simulations of binary and ternary amphiphilic fluids in two and three dimensions are used to illustrate the ...
AR Porter   +22 more
core   +1 more source

Quantum physics and computers [PDF]

open access: yesContemporary Physics, 1996
27 pages, LaTeX, 8 PostScript figures embedded. A bug in one of the postscript files has been fixed. Reprints available from the author.
openaire   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Energy deposition and deflection of α particles in hot dense plasmas relevant to inertial confinement fusions

open access: yesNuclear Fusion, 2023
Based on the kinetic theory, improved T -matrix models for the continuous-slowing-down and the linear-energy-transfer stopping powers are established at the same level, where multiple scattering effects and the related transverse deflection are accounted
Chengliang Lin   +3 more
doaj   +1 more source

Computation across the curriculum: What skills are needed?

open access: yes, 2015
Computation, the use of a computer to solve, simulate, or visualize a physical problem, has revolutionized how physics research is done. Computation is used widely to model systems, to simulate experiments, and to analyze data. Yet, in most undergraduate
Caballero, Marcos D.
core   +1 more source

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham   +14 more
wiley   +1 more source

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