Results 41 to 50 of about 186,255 (315)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Quantum algorithms for computational nuclear physics
EPJ Web of Conferences, 2015 While quantum algorithms have been studied as an efficient tool for the stationary state energy determination in the case of molecular quantum systems, no similar study for analogical problems in computational nuclear physics (computation of energy ...
Višňák Jakub
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
EntropyA univariate stochastic system driven by multiplicative Gaussian white noise is considered. The standard method for simulating its Langevin equation of motion involves incrementing the system’s state variable by a biased Gaussian random number at each ...
Mykhaylo Evstigneev, Deniz Kacmazer
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Physics computational literacy: Programming, modeling, and collaboration at the journeyman level
Physical Review Physics Education ResearchComputation has become an integral part of physics research. However, little is known about how students learn to productively use computation as a tool beyond the introductory level, especially as they transition into physics research. In this study, we
Karl Henrik Fredly +2 more
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Generation of high intensity speckles in overlapping laser beams
Matter and Radiation at Extremes, 2023 A new mechanism for the generation of high intensity speckles by coupling of overlapping beams is discovered and studied in detail. Using three-dimensional simulations, the coupling of overlapping beams smoothed by phase plates and by polarization ...
Liang Hao, Jie Qiu, Wen Yi Huo
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Quantum physics and computers [PDF]
Contemporary Physics, 1996 27 pages, LaTeX, 8 PostScript figures embedded. A bug in one of the postscript files has been fixed. Reprints available from the author.
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Frontiers in Materials, 2020 During the past two decades, the high-entropy alloy AlCoCrFeNi has attracted much attention due to its outstanding thermal and mechanical properties under ambient conditions.
Juefei Wu +8 more
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