Results 41 to 50 of about 135,074 (266)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Frontiers in Materials, 2020 During the past two decades, the high-entropy alloy AlCoCrFeNi has attracted much attention due to its outstanding thermal and mechanical properties under ambient conditions.
Juefei Wu +8 more
doaj +1 more source
Generation of high intensity speckles in overlapping laser beams
Matter and Radiation at Extremes, 2023 A new mechanism for the generation of high intensity speckles by coupling of overlapping beams is discovered and studied in detail. Using three-dimensional simulations, the coupling of overlapping beams smoothed by phase plates and by polarization ...
Liang Hao, Jie Qiu, Wen Yi Huo
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Nuclear Fusion, 2023 Based on the kinetic theory, improved T -matrix models for the continuous-slowing-down and the linear-energy-transfer stopping powers are established at the same level, where multiple scattering effects and the related transverse deflection are accounted
Chengliang Lin +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Active learning algorithm for computational physics
Physical Review Research, 2020 In large-scale computations of physical problems, one often encounters the situation of having to determine a multidimensional function, which can be numerically costly when computing each point in this multidimensional space is already time-demanding ...
Juan Yao +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Linear analysis of Atwood number effects on shear instability in the elastic–plastic solids
Scientific Reports, 2021 The evolution of shear instability between elastic–plastic solid and ideal fluid which is concerned in oblique impact is studied by developing an approximate linear theoretical model.
Xi Wang +4 more
doaj +1 more source