Results 21 to 30 of about 33,138 (231)

Computational Psychiatry [PDF]

open access: yesNeuron, 2014
Psychiatric disorders such as autism and schizophrenia, arise from abnormalities in brain systems that underlie cognitive, emotional, and social functions. The brain is enormously complex and its abundant feedback loops on multiple scales preclude intuitive explication of circuit functions.
Wang, Xiao-Jing, Krystal, John H.
openaire   +2 more sources

Computational psychiatry [PDF]

open access: yesTrends in Cognitive Sciences, 2012
Computational ideas pervade many areas of science and have an integrative explanatory role in neuroscience and cognitive science. However, computational depictions of cognitive function have had surprisingly little impact on the way we assess mental illness because diseases of the mind have not been systematically conceptualized in computational terms.
Montague, P.   +3 more
openaire   +4 more sources

Reconceptualising the DSM: Neuroanalysis and digital brain profiling

open access: yesEuropean Psychiatry, 2021
Recent years have seen a great advancement in the emerging field of Neural Computation, a study of the brain using neuronal network models. As a consequence, another field of science is being developed titled ‘Computational Psychiatry’ where neuronal ...
A. Peled
doaj   +1 more source

Modules for Automated Validation and Comparison of Models of Neurophysiological and Neurocognitive Biomarkers of Psychiatric Disorders: ASSRUnit—A Case Study [PDF]

open access: yesComputational Psychiatry, 2018
The characterization of biomarkers has been a central goal of research in psychiatry over the last years. While most of this research has focused on the identification of biomarkers, using various experimental approaches, it has been recognized that ...
Christoph Metzner   +3 more
doaj   +2 more sources

Generative models as computational assays for psychiatry

open access: yesEuropean Psychiatry, 2023
Psychiatry faces fundamental challenges with regard to mechanistically guided differential diagnosis, as well as prediction of clinical trajectories and treatment response.
S. Frässle
doaj   +1 more source

Overcoming Pavlovian bias in semantic space

open access: yesScientific Reports, 2021
Action is invigorated in the presence of reward-predicting stimuli and inhibited in the presence of punishment-predicting stimuli. Although valuable as a heuristic, this Pavlovian bias can also lead to maladaptive behaviour and is implicated in addiction.
Sam Ereira   +4 more
doaj   +1 more source

Assigning the right credit to the wrong action: compulsivity in the general population is associated with augmented outcome-irrelevant value-based learning

open access: yesTranslational Psychiatry, 2021
Compulsive behavior is enacted under a belief that a specific act controls the likelihood of an undesired future event. Compulsive behaviors are widespread in the general population despite having no causal relationship with events they aspire to ...
Nitzan Shahar   +6 more
doaj   +1 more source

Social training reconfigures prediction errors to shape Self-Other boundaries

open access: yesNature Communications, 2020
The human brain can simulate other people’s mental processes with Self-specific and Other-specific neural circuits, but it is not known how these circuits emerge. Here, the authors show that these circuits adapt to social experience, to determine whether
Sam Ereira   +5 more
doaj   +1 more source

Representation of probabilistic outcomes during risky decision-making

open access: yesNature Communications, 2020
Goal directed behavior requires the sequential retrieval and evaluation of the multiple choices for action and their deterministic outcomes. Here, the authors report sequential, decodable probabilistic outcome representations in magnetoencephalography ...
Giuseppe Castegnetti   +6 more
doaj   +1 more source

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