Results 71 to 80 of about 8,980,708 (398)

Natural Language Processing at the School of Information Studies for Africa [PDF]

open access: yes, 2005
The lack of persons trained in computational linguistic methods is a severe obstacle to making the Internet and computers accessible to people all over the world in their own languages.
Eriksson, Gunnar   +2 more
core   +1 more source

An Investigation of Students’ Use of a Computational Science Simulation in an Online High School Physics Class

open access: yesEducation Sciences, 2019
Science educators have begun to explore how students have opportunities to not only view and manipulate simulations, but also to analyze the complex sources of data they generate.
Joshua M. Rosenberg, Michael A. Lawson
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Rethinking resource allocation in science

open access: yesEcology and Society, 2019
Many funding agencies rely on grant proposal peer review to allocate scientific funding, i.e., researchers compete for funding by submitting proposals that are reviewed and ranked by committees of their peers.
Johan Bollen   +3 more
doaj   +1 more source

How Computational Modeling Can Force Theory Building in Psychological Science

open access: yesPerspectives on Psychological Science, 2020
Psychology endeavors to develop theories of human capacities and behaviors on the basis of a variety of methodologies and dependent measures. We argue that one of the most divisive factors in psychological science is whether researchers choose to use ...
Olivia Guest, Andrea E. Martin
semanticscholar   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

A Workflow for Software Development within Computational Epidemiology [PDF]

open access: yes, 2011
A critical investigation into computational models developed for studying the spread of communicable disease is presented. The case in point is a spatially explicit micro-meso-macro model for the entire Swedish population built on registry data, thus far
Abramson   +22 more
core   +2 more sources

Integration of Python into Science Teacher Education, Developing Computational Problem Solving and Using Information and Communication Technologies Competencies of Pre-service Science Teachers

open access: yesInformatics in Education, 2022
This study reports the findings of a program that aims to develop pre-service science teachers’ computational problem-solving skills and views on using information and communications technology in science education.
Kaan BATI
doaj   +1 more source

Data Science in Perspective [PDF]

open access: yesarXiv, 2022
Data and Science has stood out in the generation of results, whether in the projects of the scientific domain or business domain. CERN Project, Scientific Institutes, companies like Walmart, Google, Apple, among others, need data to present their results and make predictions in the competitive data world.
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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