Results 51 to 60 of about 624,297 (264)

MANIFESTO OF COMPUTATIONAL SOCIAL SCIENCE

Mediações: Revista de Ciências Sociais, 2013
The increasing integration of technology into our lives has created unprecedented volumes of data on society’s everyday behaviour. Such data opens up exciting new opportunities to work towards a quantitative understanding of our complex social systems ...
Rosaria Conte, Nigel Gilbert, Giullia Bonelli, Claudio Cioffi-Revilla, Guillaume Deffuant, János Kertész, Vittorio Loreto, Suzy Moat, Jean-Pierre Nadal, Ángel Sánchez, Andrzej Nowak, Andreas Flache, Maxi San Miguel, Dirk Helbing   +13 more
doaj   +1 more source

Ubiquity symposium: The science in computer science: natural computation [PDF]

Ubiquity, 2014
In this twelfth piece of the Ubiquity symposium discussing science in computer science, Erol Gelenbe reviews computation in natural systems, focusing mainly on biology and citing examples of the computation that is inherent in chemistry, natural selection, gene regulatory networks, and neuronal systems.
openaire   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Computational materials science

Moldavian Journal of the Physical Sciences, 2014
First-principles simulation, meaning density-functional theory calculations with plane waves and pseudopotentials, has become a prized technique in condensed-matter theory.
Nazarov, Mihail, Arellano, I.
doaj  

CICT: New Eyes on Computational Competence in Computational Science

ITM Web of Conferences, 2018
Science does not exists to enlighten people's minds only. It mainly exists to show the educated way from quanta to qualia. And that way starts from computational competence. In previous papers published elsewhere, we have already shown that traditional Q
Fiorini Rodolfo A.
doaj   +1 more source

Special Issue “Computational Social Science”

Information, 2019
The last centuries have seen a great surge in our understanding and control of “simple” physical, chemical, and biological processes through data analysis and the mathematical modeling of their underlying dynamics [...]
Gerardo Iñiguez, Hang-Hyun Jo, Kimmo Kaski   +2 more
doaj   +1 more source

Ubiquity symposium: The science in computer science: the computing sciences and STEM education [PDF]

Ubiquity, 2014
In this latest installment of "The Science in Computer Science," Prof. Paul Rosenbloom continues the discussion on whether or not computer science can be considered a "natural science." He argues not only is computing the basis for a true science, it is in fact an entire scientific domain.
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source