Results 81 to 90 of about 2,948,294 (361)

Using Graphing Calculators to Integrate Mathematics and Science [PDF]

, 1997
The computational, graphing, statistical and programming capabilities of today’s graphing calculators make it possible for teachers and students to explore aspects of functions and investigate real-world situations in ways that were previously ...
Garofalo, J., Pullano, F.
core   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

Mathematical Logic in Computer Science [PDF]

arXiv, 2018
The article retraces major events and milestones in the mutual influences between mathematical logic and computer science since the 1950s.
arxiv  

A Workflow for Software Development within Computational Epidemiology [PDF]

, 2011
A critical investigation into computational models developed for studying the spread of communicable disease is presented. The case in point is a spatially explicit micro-meso-macro model for the entire Swedish population built on registry data, thus far
Abramson, Axtell, Balcan, Boman, Bonabeau, Brouwers, Cakici, Chao, Coelho, Crubezy, Epstein, Espino, Eubank, Ferguson, Halloran, Kermack, Longini, Newman, Popper, Roche, Ross, Thom, Youssef   +22 more
core   +2 more sources

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Multiple sclerosis clinical decision support system based on projection to reference datasets

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1863-1873, December 2022., 2022
Abstract Objective Multiple sclerosis (MS) is a multifactorial disease with increasingly complicated management. Our objective is to use on‐demand computational power to address the challenges of dynamically managing MS. Methods A phase 3 clinical trial data (NCT00906399) were used to contextualize the medication efficacy of peg‐interferon beta‐1a vs ...
Chadia Ed‐driouch, Florent Chéneau, Françoise Simon, Guillaume Pasquier, Benoit Combès, Anne Kerbrat, Emmanuelle Le Page, Sophie Limou, Nicolas Vince, David‐Axel Laplaud, Franck Mars, Cédric Dumas, Gilles Edan, Pierre‐Antoine Gourraud   +13 more
wiley   +1 more source

Defining Data Science [PDF]

arXiv, 2015
Data science is gaining more and more and widespread attention, but no consensus viewpoint on what data science is has emerged. As a new science, its objects of study and scientific issues should not be covered by established sciences. Data in cyberspace have formed what we call datanature.
arxiv  

Ubiquity symposium: The science in computer science: unplugging computer science to find the science [PDF]

Ubiquity, 2014
The Computer Science Unplugged project provides activities that enable students to engage with concepts from computer science without having to program. Many of the activities provide the basis of a scientific exploration of computer science, and thus help students to see the relationship of the discipline with science.
openaire   +3 more sources

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

The Complexity of Rooted Phylogeny Problems [PDF]

Logical Methods in Computer Science, 2011
Several computational problems in phylogenetic reconstruction can be formulated as restrictions of the following general problem: given a formula in conjunctive normal form where the literals are rooted triples, is there a rooted binary tree that ...
Manuel Bodirsky, Jens K Mueller
doaj   +1 more source