Results 81 to 90 of about 39,144,787 (249)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
InformaticsThis paper presents a comprehensive analysis of the social media posts of prefectural governors in Japan during the COVID-19 pandemic. It investigates the correlation between social media activity levels, governors’ characteristics, and engagement ...
Salama Shady +2 more
doaj +1 more source
Preface: Computational Science – ICCS 2025 Workshops
The 6-volume set constitutes the workshop proceedings of the 25th International Conference on Computational Science, ICCS 2025, which took place in Singapore, Singapore, during July 7–9, 2025. The 137 full papers and 32 short papers presented in these
Barnard, Amanda S. +2 more
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Methodological Innovations, 2016 Today’s world allows people to connect over larger distances and in shorter intervals than ever before, widely monitored by massive online data sources.
Raphael H. Heiberger, Jan R. Riebling
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Topological enslavement in evolutionary games on correlated multiplex networks
New Journal of Physics, 2018 Governments and enterprises strongly rely on incentives to generate favorable outcomes from social and strategic interactions between individuals. The incentives are usually modeled by payoffs in evolutionary games, such as the prisoners dilemma or the ...
Kaj-Kolja Kleineberg, Dirk Helbing
doaj +1 more source
Bot stamina: examining the influence and staying power of bots in online social networks
Applied Network Science, 2019 This study presents a novel approach to expand the emergent area of social bot research. We employ a methodological framework that aggregates and fuses data from multiple global Twitter conversations with an available bot detection platform and ...
Ross Schuchard +3 more
doaj +1 more source
Los Angeles County Social Survey, 1995 (LACSS)
The Los Angeles County Social Survey (LACSS) continues the Los Angeles Metropolitan Area Studies (LAMAS) and the Southern California Social Surveys (SCSS).
University of California, Los Angeles. Institute for Social Science Research.
core +2 more sources
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source