Results 71 to 80 of about 3,869,880 (334)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Solutions of fractional differential equations by using a blend of variational iteration method with Sumudu transform and application to price adjustment equations

open access: yesPartial Differential Equations in Applied Mathematics, 2023
The presence of delays in a mathematical model can improve its vitality and suitability in describing several phenomena. However, in the presence of delays, nonlinear fractional differential equations are more difficult to study.
M.O. Aibinu, S. Moyo
doaj  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Computational Thinking and Modeling: A Quasi-Experimental Study of Learning Transfer

open access: yesEducation Sciences
This quasi-experimental study investigated the impact of computational learning activities on high school students’ computational thinking (CT) and computational modeling (CM) skills.
Line Have Musaeus, Peter Musaeus
doaj   +1 more source

Rethinking Computational Thinking for Public Libraries' Youth Programs: Challenges and Recommendations

open access: yesPennsylvania Libraries: Research & Practice, 2018
Computational thinking has become a popular and important concept in education throughout the nation. Public libraries, with their technology services and their role as an informal learning space, have been tagged as an ideal place for computational ...
Marissa Guidara
doaj   +1 more source

Review on the teaching of programming and computational thinking in the world

open access: yesFrontiers of Computer Science, 2022
Recent studies suggest that computational thinking, composed of the skills of abstraction, decomposition, algorithmization, debugging, and problem-solving, is the fundamental skill for scientific, technological, and economic development for the twenty ...
Héctor Belmar
semanticscholar   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

LatEval: An Interactive LLMs Evaluation Benchmark with Incomplete Information from Lateral Thinking Puzzles [PDF]

open access: yesarXiv, 2023
With the continuous evolution and refinement of LLMs, they are endowed with impressive logical reasoning or vertical thinking capabilities. But can they think out of the box? Do they possess proficient lateral thinking abilities? Following the setup of Lateral Thinking Puzzles, we propose a novel evaluation benchmark, LatEval, which assesses the model ...
arxiv  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Sex classification of 3D skull images using deep neural networks

open access: yesScientific Reports
Determining the fundamental characteristics that define a face as "feminine" or "masculine" has long fascinated anatomists and plastic surgeons, particularly those involved in aesthetic and gender-affirming surgery.
Lake Noel   +10 more
doaj   +1 more source

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