Results 91 to 100 of about 73,306 (292)

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

A new approach methodology to identify tumorigenic chemicals using short-term exposures and transcript profiling

Frontiers in Toxicology
Current methods for cancer risk assessment are resource-intensive and not feasible for most of the thousands of untested chemicals. In earlier studies, we developed a new approach methodology (NAM) to identify liver tumorigens using gene expression ...
Victoria Ledbetter, Victoria Ledbetter, Scott Auerbach, Logan J. Everett, Beena Vallanat, Anna Lowit, Gregory Akerman, William Gwinn, Leah C. Wehmas, Michael F. Hughes, Michael Devito, J. Christopher Corton   +11 more
doaj   +1 more source

A Multi-Level Analysis of World Scientific Output in Pharmacology [PDF]

, 2012
The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database.
Olmeda-Gómez, Carlos, Ovalle-Perandones, María-Antonia, Perianes-Rodríguez, Antonio   +2 more
core  

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Integrated Evaluation of Contaminant Profiles, Detection Techniques, and Management Strategies for Tannery Sludge

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This review article critically examines the environmental and health hazards of tannery sludge (TS), a complex by‐product of the leather tanning industry. TS is characterized by a diverse array of contaminants, including heavy metals like chromium, organic pollutants such as polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds ...
Yashar Aryanfar, Ali Keçebaş, Soheil Hassanzadeh, Arash Nourbakhsh Sadabad, Farhan Lafta Rashid, Shabbir Ahmad, Ahmed Hendy, Hafiz M. Irfan, Shaban Mousavi Ghasemlou, Julio Blanco Fernandez, Jorge Luis Garcia Alcaraz   +10 more
wiley   +1 more source

A Novel Machine Learning Model and a Web Portal for Predicting the Human Skin Sensitization Effects of Chemical Agents

Toxics
Skin sensitization is a significant concern for chemical safety assessments. Traditional animal assays often fail to predict human responses accurately, and ethical constraints limit the collection of human data, necessitating a need for reliable in ...
Ricardo Scheufen Tieghi, José Teófilo Moreira-Filho, Holli-Joi Martin, James Wellnitz, Miguel Canamary Otoch, Marielle Rath, Alexander Tropsha, Eugene N. Muratov, Nicole Kleinstreuer   +8 more
doaj   +1 more source

Enhanced Rheological and Filtration Performance of Drilling Fluids Using Fe3O4/Saponin/Cu(II) Nanocomposites: Synthesis, Characterization, and Application

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Drilling fluids used in high‐performance well operations often struggle to maintain rheological stability, colloidal dispersion, and filtration control under harsh downhole conditions. This study engineered a multifunctional Fe3O4@Saponin/Cu(II) nanocomposite to address these challenges.
Kassem Al Attabi, Farag M. A. Altalbawy, Hana Ihsan Hassan, Ahmed Salih Sahib, Zahraa Saad Abdulali, Mariem Alwan, Mahmood Jawad, Hiba Mushtaq, Aseel Smerat, Fatimah Pashtun   +9 more
wiley   +1 more source

The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

Scientific Data
Since the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to ...
Sakshi Handa, Kristin K. Isaacs, Jonathan T. Wall, Allison Larger, Scott Burns, Lauren E. Koval, Kenta Baron-Furuyama, Colleen M. Elonen, David Lyons, Kathie L. Dionisio, M. Beth Horton, Katherine A. Phillips   +11 more
doaj   +1 more source

Advances in Regulating Strategies and Applications of Ferroelectric Materials

Advanced Physics Research, EarlyView.
To meet the demand for precise control of performance in nanoelectronic devices, this paper systematically reviews the latest advances in controlling ferroelectric properties through strategies such as external field modulation, low‐dimensional confinement, interface engineering, and topological structure design.
Jianying Ji, Cong Liu, Dan Luo, Zhou Li
wiley   +1 more source