Results 91 to 100 of about 72,918 (293)

A Novel Machine Learning Model and a Web Portal for Predicting the Human Skin Sensitization Effects of Chemical Agents

Toxics
Skin sensitization is a significant concern for chemical safety assessments. Traditional animal assays often fail to predict human responses accurately, and ethical constraints limit the collection of human data, necessitating a need for reliable in ...
Ricardo Scheufen Tieghi, José Teófilo Moreira-Filho, Holli-Joi Martin, James Wellnitz, Miguel Canamary Otoch, Marielle Rath, Alexander Tropsha, Eugene N. Muratov, Nicole Kleinstreuer   +8 more
doaj   +1 more source

In silico toxicology models and databases as FDA Critical Path Initiative toolkits

Human Genomics, 2011
In silico toxicology methods are practical, evidence-based and high throughput, with varying accuracy. In silico approaches are of keen interest, not only to scientists in the private sector and to academic researchers worldwide, but also to the public ...
Valerio Luis G
doaj   +1 more source

Bis(2‐amino‐5‐thienyl)Ketone as Oxygen Tolerant Sensitizer for Conventional Radical Photopolymerization

Angewandte Chemie International Edition, EarlyView.
Bis(2‐amino‐5‐thienyl)ketones operate as sensitizer in multi‐component photoinitiating systems using either diaryl iodonium cation or amino benzoates as coinitiators to initiate conventional radical polymerization following either oxidative or reduction photoinduced electron transfer protocol, respectively.
Taner Poplata, Qunying Wang, Xavier Allonas, Martin Jäger, Jochen S. Gutmann, Evgenia Dmitrieva, Horst Hartmann, Bernd Strehmel   +7 more
wiley   +1 more source

The Chemical and Products Database v4.0, an updated resource supporting chemical exposure evaluations

Scientific Data
Since the initial release of the Chemical and Products Database (CPDat) in 2018, the United States Environmental Protection Agency has added a considerable amount of chemical exposure-related information to the database and has expanded its schema to ...
Sakshi Handa, Kristin K. Isaacs, Jonathan T. Wall, Allison Larger, Scott Burns, Lauren E. Koval, Kenta Baron-Furuyama, Colleen M. Elonen, David Lyons, Kathie L. Dionisio, M. Beth Horton, Katherine A. Phillips   +11 more
doaj   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

Comprehensive computational analysis via Adverse Outcome Pathways and Aggregate Exposure Pathways in exploring synergistic effects from radon and tobacco smoke on lung cancer

Frontiers in Public Health
Lung cancer remains the leading cause of cancer mortality worldwide, with tobacco smoke and radon exposure being the primary risk factors. The interaction between these two factors has been described as sub-multiplicative, but a better understanding is ...
Thomas Jaylet, Vinita Chauhan, Laura Mezquita, Nadia Boroumand, Olivier Laurent, Karine Elihn, Lovisa Lundholm, Olivier Armant, Karine Audouze   +8 more
doaj   +1 more source

Particle deposition onto a flat plate with various slopes [PDF]

, 2003
In this work, a numerical simulation of the deposition of small suspended particles onto a flat plate with various degrees of inclination is performed.
Miguel, A. F., Silva, A. M.
core  

Integrated Evaluation of Contaminant Profiles, Detection Techniques, and Management Strategies for Tannery Sludge

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This review article critically examines the environmental and health hazards of tannery sludge (TS), a complex by‐product of the leather tanning industry. TS is characterized by a diverse array of contaminants, including heavy metals like chromium, organic pollutants such as polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds ...
Yashar Aryanfar, Ali Keçebaş, Soheil Hassanzadeh, Arash Nourbakhsh Sadabad, Farhan Lafta Rashid, Shabbir Ahmad, Ahmed Hendy, Hafiz M. Irfan, Shaban Mousavi Ghasemlou, Julio Blanco Fernandez, Jorge Luis Garcia Alcaraz   +10 more
wiley   +1 more source

Artificial Intelligence and Machine Learning Models for Predicting Drug-Induced Kidney Injury in Small Molecules

Pharmaceuticals
Background/Objectives: Drug-Induced Kidney Injury (DIKI) presents a significant challenge in drug development, often leading to clinical-stage failures. The early prediction of DIKI risk can improve drug safety and development efficiency. Existing models
Mohan Rao, Vahid Nassiri, Sanjay Srivastava, Amy Yang, Satjit Brar, Eric McDuffie, Clifford Sachs   +6 more
doaj   +1 more source

2018 State-of the Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Eco-Toxicity and Sublethal Impacts [PDF]

, 2018
Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center (CRRC)
core   +1 more source