Results 131 to 140 of about 3,045,461 (301)

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Editorial: Application of computational tools to health and environmental sciences, Volume II

Frontiers in Pharmacology, 2022
Patricia Ruiz, George Loizou
doaj   +1 more source

Chemical and Product Categories (CPCat) database

, 2019
The EPA CPCat (Chemical and Product Categories) database was released in May 2014. It maps >43,000 chemicals to a set of terms categorizing their usage or function. We have compiled a comprehensive list of chemicals with associated categories of chemical
EPA's National Center for Computational Toxicology (5039467)
core   +1 more source

The influence of rivers on seabird foraging ecology

Biological Reviews, EarlyView.
ABSTRACT Rivers act as vital arteries to the world's oceans, delivering fresh water and nutrients that sustain marine ecosystems. Globally, river flow increasingly is being altered by climate change and anthropogenic pressures; yet the significance of rivers to predatory marine species, such as seabirds, and the extent to which river‐related changes ...
Julia B. Morais, Andre Chiaradia, Richard D. Reina   +2 more
wiley   +1 more source

Decoding cellular stress states for toxicology using single-cell transcriptomics

NAM Journal
We applied the TempO-LINC® platform to generate single-cell transcriptomic (SCTr) profiles of ∼40,000 HepaRG cells exposed to etoposide, brefeldin A, cycloheximide, rotenone, tBHQ, troglitazone, and tunicamycin at three concentrations for 24 hours.
Imran Shah, David Gallegos, Brian Robinette, Bryant A. Chambers, Dennis J. Eastburn, Douglas A. Bell, Michelle R. Campbell, Suzanne N. Martos, Salvatore Camiolo, Kevin S. White, Nicole Martin, Gioele Montis, Joel McComb, Bruce Seligmann, Brian N. Chorley   +14 more
doaj   +1 more source

Stakeholder Engagement as a Design Principle: Orchestrating a Digital Platform for the Safety and Sustainability of the Nanomaterials Sector

Business Strategy and the Environment, EarlyView.
ABSTRACT The governance of chemicals and nanomaterials presents a critical challenge, as significant uncertainties regarding safety and sustainability match their innovation potential. This creates a “knowledge‐to‐action” gap, hindering the practical implementation of safety and sustainability by design (SSbD) principles.
Mario Miozza, Luigi Mersico, Jelena Barbir, Genc Alimehmeti, Angelo Paletta   +4 more
wiley   +1 more source

ctxR: Utilities for interacting with the CTX APIs

NAM Journal
A new R package, ctxR, is presented. ctxR is an open-source R Client package used to interact with the Computational Toxicology and Exposure Application Programming Interfaces (CTX APIs) in R.
Paul M. Kruse, Caroline L. Ring, Katie Paul Friedman, Madison Feshuk, Jason Brown, Carter Thunes, Asif Rashid   +6 more
doaj   +1 more source

Reporting What Matters, or Reporting What Looks Good? Materiality and Balance in Post–Rana Plaza Apparel Sustainability Disclosure

Business Strategy and the Environment, EarlyView.
ABSTRACT Sustainability reports (SRs) are widely criticized for vague disclosures and selective emphasis on positive outcomes, yet systematic research on two core SR challenges remains limited: materiality (whether disclosed content is relevant) and balance (whether both achievements and challenges are reported).
Mahsa Mohammadrezaei, José Carlos Marques   +1 more
wiley   +1 more source

The Role of Simulation Science in Public Health at the Agency for Toxic Substances and Disease Registry: An Overview and Analysis of the Last Decade

Toxics
Environmental exposures are ubiquitous and play a significant, and sometimes understated, role in public health as they can lead to the development of various chronic and infectious diseases. In an ideal world, there would be sufficient experimental data
Siddhi Desai, Jewell Wilson, Chao Ji, Jason Sautner, Andrew J. Prussia, Eugene Demchuk, M. Moiz Mumtaz, Patricia Ruiz   +7 more
doaj   +1 more source

Book Review: Computational Toxicology. Risk Assessment for Pharmaceutical and Environmental Chemicals, 2nd Edition [PDF]

Front Pharmacol, 2019
Book Review: Computational Toxicology.
Marcelo T de Oliveira (19450078)
europepmc   +1 more source