Results 71 to 80 of about 1,850,989 (303)

Fibre and failure characterization in long glass fibre reinforced polypropylene by X-ray computed tomography

Polymer Testing
Long fibre reinforced thermoplastics (LFTs) have become important in recent years, due to outstanding mechanical properties (such as high strength, high stiffness, and excellent impact behaviour).
Julia Maurer, Dietmar Salaberger, Michael Jerabek, Bernhard Fröhler, Johann Kastner, Zoltán Major   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Relationships between lamb carcass quality traits measured by X-ray computed tomography (CT) and current UK-hill sheep breeding goals. [PDF]

, 2008
Genetic parameters were estimated between current UK hill sheep breeding goals and lamb carcass composition and muscularity traits derived using X-ray computed tomography (CT).
McLean, KA, McLaren, A., Lambe, NR; id_orcid, Bishop, S. C., Simm, Geoff, Lambe, N. R., Bünger, L., McLean, K. A., Conington, JE; id_orcid, McLaren, A; id_orcid, Bishop, SC, Simm, G, Bunger, L, Conington, J.   +13 more
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Dual-layer spectral detector computed tomography multiparameter machine learning model for prediction of lymph node metastases in esophageal squamous cell carcinoma

Cancer Imaging
Objective Accurate assessment of lymph node metastasis (LNM) is essential for the staging, treatment, and prognosis of esophageal squamous cell carcinoma (ESCC).
Junjie Zhang, Ligang Hao, Peiyi Ma, Qiuxu Zhang, Linyi Jia, Fengxiao Gao   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Prediction of lymphovascular invasion in esophageal squamous cell carcinoma by computed tomography-based radiomics analysis: 2D or 3D ?

Cancer Imaging
Background To compare the performance between one-slice two-dimensional (2D) and whole-volume three-dimensional (3D) computed tomography (CT)-based radiomics models in the prediction of lymphovascular invasion (LVI) status in esophageal squamous cell ...
Yang Li, Xiaolong Gu, Li Yang, Xiangming Wang, Qi Wang, Xiaosheng Xu, Andu Zhang, Meng Yue, Mingbo Wang, Mengdi Cong, Jialiang Ren, Wei Ren, Gaofeng Shi   +12 more
doaj   +1 more source

Fast Image Segmentation Using Two-Dimensional Otsu Based on Estimation of Distribution Algorithm

Journal of Electrical and Computer Engineering, 2017
Traditional two-dimensional Otsu algorithm has several drawbacks; that is, the sum of probabilities of target and background is approximate to 1 inaccurately, the details of neighborhood image are not obvious, and the computational cost is high. In order
Wuli Wang, Liming Duan, Yong Wang
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source