Results 101 to 110 of about 593,691 (360)

Computer-aided molecular design

open access: yesComputer-Aided Design, 1985
Abstract Computer-aided molecular design has come of age. In the pharmaceutical and fine chemical industries computer graphics techniques allied to theoretical calculations are proving successful in suggesting to synthetic chemists molecules which will merit synthesis in terms of desired specific properties.
openaire   +3 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Magnetic Flux Sensor Based on Spiking Neurons with Josephson Junctions

open access: yesSensors
Josephson junctions (JJs) are superconductor-based devices used to build highly sensitive magnetic flux sensors called superconducting quantum interference devices (SQUIDs).
Timur Karimov   +5 more
doaj   +1 more source

A bibliography on digital computer-aided circuit analysis and design [PDF]

open access: yes
Digital computer-aided electric logic circuit analysis and design ...
Yang, T.
core   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Современные подходы в 3D моделировании ортезных приспособлений [PDF]

open access: yes, 2014
Рассмотрены технологические решения моделирования и изготовления ортезных приспособлений с использованием систем автоматизированного проектирования группы CAD (Computer Aided Design) – CAM (Computer Aided Design).The technological decisions of design and
Носов, П. С.   +1 more
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Time-Series Feature Extraction by Return Map Analysis and Its Application to Bearing-Fault Detection

open access: yesBig Data and Cognitive Computing
Developing new features for time-series characterization is a current challenge in data science and machine learning. In this paper, we propose a new metric based on a simple and efficient algorithm, namely, the return map.
Veronika Ponomareva   +6 more
doaj   +1 more source

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