Results 81 to 90 of about 613,456 (310)

MMTransformer: a multivariate time-series resource forecasting model for multi-component applications

open access: yesScientific Reports
Efficient resource forecasting in multi-component application scenarios necessitates comprehensive consideration of inter-component dependencies and resource interaction characteristics.
Guangzhang Cui   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Geometric modeling for computer-aided design [PDF]

open access: yes
Software was developed to be used with the derivation of smooth three dimensional surfaces from a sequence of cross sections. Problems arising in the creation of surfaces by extrusion are considered and calculated physical properties are ...
Schwing, James L., Spangler, Jan
core   +1 more source

Computer-aided design (CAD) [PDF]

open access: yes, 2015
Acronimo di Computer-Aided Design (progettazione assistita da elaboratore). È una famiglia di procedure e software di tipo vettoriale, utilizzati per il disegno architettonico e meccanico, per il rilievo di oggetti ed ...
EMPLER, TOMMASO
core  

Computer-aided molecular design

open access: yesComputer-Aided Design, 1985
Abstract Computer-aided molecular design has come of age. In the pharmaceutical and fine chemical industries computer graphics techniques allied to theoretical calculations are proving successful in suggesting to synthetic chemists molecules which will merit synthesis in terms of desired specific properties.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Exploratory Landscape Validation for Bayesian Optimization Algorithms

open access: yesMathematics
Bayesian optimization algorithms are widely used for solving problems with a high computational complexity in terms of objective function evaluation. The efficiency of Bayesian optimization is strongly dependent on the quality of the surrogate models of ...
Taleh Agasiev, Anatoly Karpenko
doaj   +1 more source

Parametric modelling of Malaysian teeth template using computer aided design [PDF]

open access: yes, 2016
This study explored a new method and process of design denture using CAD technology to develop a template of a complete denture. Computer aided design were used as a tool of the design process.
ABAS, NOR HASLINDA   +4 more
core   +4 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Joint Center Estimation Using Single-Frame Optimization: Part 1: Numerical Simulation

open access: yesSensors, 2018
The biomechanical models used to refine and stabilize motion capture processes are almost invariably driven by joint center estimates, and any errors in joint center calculation carry over and can be compounded when calculating joint kinematics ...
Eric Frick, Salam Rahmatalla
doaj   +1 more source

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