Revolutionizing dental restorations: Insights into computer-aided design/computer-aided manufacturing materials - A systematic review. [PDF]
Ramnarayan BK +5 more
europepmc +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Customized positioning of the glenoid component in reverse shoulder arthroplasty: a new computer aided design methodology. [PDF]
Cirello A +8 more
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Defining the influence of digitalization on the future of dentistry through an educational handbook for Computer Aided Design tool training. [PDF]
Anghel MA +10 more
europepmc +1 more source
Threonine 348 regulates the subcellular localization of PTEN
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM)-Assisted Prosthetic Rehabilitation When Physiologic Anterior Guidance Cannot Be Re-established in a Skeletal Class III Patient: A Clinical Case Report. [PDF]
Elmfeddal K, Samadi A, El Yamani A.
europepmc +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Redesigning Computer-aided Design and Manufacturing Guides for Mandibular Reconstruction: Dental Reference Cap and Synchronized Screw-Hole Guides. [PDF]
Yen CH, Lee JJ, Wee SJ.
europepmc +1 more source
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source

