ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo+11 more
wiley +1 more source
Computer-Aided Design to Improve the Thermal Stability of Rhizomucor miehei Lipase. [PDF]
Teng R, Zhang J, Tu Z, He Q, Li Y.
europepmc +1 more source
IPAD: A unique approach to government/industry cooperation for technology development and transfer [PDF]
A key element to improved industry productivity is effective management of Computer Aided Design / Computer Aided Manufacturing (CAD/CAM) information. To stimulate advancement, a unique joint government/industry project designated Integrated Programs for
Fulton, Robert E., Salley, George C.
core +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach+11 more
wiley +1 more source
Comparative Evaluation of Fracture Resistance in Implant-Supported Provisional Crowns Fabricated by Computer-Aided Design and Manufacturing, Three-Dimensional Printing, and Conventional Self-Curing. [PDF]
Shekhar A+5 more
europepmc +1 more source
A common geometric data-base approach for computer-aided manufacturing of wind-tunnel models and theoretical aerodynamic analysis [PDF]
A more automated process to produce wind tunnel models using existing facilities is discussed. A process was sought to more rapidly determine the aerodynamic characteristics of advanced aircraft configurations.
Cozzolongo, J. V., See, M. J.
core +1 more source
THE COMPUTER AIDED DESIGN OF THE COULTER DISC FOR NO-TILLAGE MACHINES
Ovidiu RANTA+4 more
openalex +2 more sources
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos+11 more
wiley +1 more source
A Multi-Disciplinary Approach to Managing Anterior Aesthetics: Crown Lengthening/Digital Smile Design (DSD)/Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM). [PDF]
Kouji S, El Yamani A.
europepmc +1 more source