Results 111 to 120 of about 12,983,542 (274)
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Big Data Mining and AnalyticsThis study systematically investigates the roles of messenger RNAs (mRNAs) and microRNAs (miRNAs) in Renal Cell Carcinoma (RCC) and their potential as diagnostic and prognostic biomarkers via a stratification approach.
Jiaqi Yu +6 more
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Exploring the possibilities of a virtual reality aided architectural design system [PDF]
39th Conference on Education and Research in Computer Aided Architectural Design in Europe, 8th-10th September 2021, Novi Sad, Serbia, Faculty of Technical Sciences, University of Novi Sad202505 bcchVersion of RecordOthers国家自然科学基金青年科学基金 The Young ...
Lin, C, Hu, X, Lo, T
core +1 more source
Computer-Aided Drug Design and Drug Discovery: A Prospective Analysis. [PDF]
Pharmaceuticals (Basel), 2023 Niazi SK, Mariam Z.
europepmc +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
26th International Conference of the Association for Computer-Aided Architectural Design Research in Asia (CAADRIA 2020), Online and Global – Organised from Hong Kong, 29.03 - 01.04.2021202505 bcchVersion of RecordRGCPublishedCopyright retained by ...
Lo, TT, Han, Y, Qi, X
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
From HCI to HVRI : how different will the interaction of digital architecture design be?
25th International Conference of the Association for Computer-Aided Architectural Design Research in Asia (CAADRIA 2021), 5-6 August 2020, Faculty of Architecture, Chulalongkorn University, Bangkok, Thailand202505 bcchVersion of ...
Lo, TT, Gao, X
core +1 more source
Scientific ReportsNatural products (NPs) are secondary metabolites that exert their biological effects within and on other organisms. Bacteria are considered potent producers of bioactive natural compounds, due to their versatile biocatalytic activity.
Anushka Bhrdwaj +2 more
doaj +1 more source