Results 101 to 110 of about 13,701,591 (243)

Computer-aided vaccine design /

Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study.
Ranganathan, Shoba,author., Chuan, Tong Joo,author.   +1 more
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Designing 'action trigger' for architecture modelling design within immersive virtual reality

24th International Conference of the Association for Computer-Aided Architectural Design Research in Asia (CAADRIA 2019), April 15th-18th 2019, Faculty of Architecture & Design, Victoria University of Wellington, Wellington, New Zealand202505 bcchVersion
Yu, H, Lo, TT, Xiao, Z
core   +1 more source

Computer-aided design (CAD) model.

, 2019
Computer-aided design (CAD) model.
Adham E. Ragab (6565115), Tamer M. Khalaf (6565121), Mohamed A. Saleh (6565112), Abdulmajeed Dabwan (6565118), Usama Umer (6565124), Atef M. Ghaleb (6565109)   +5 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

ELECTROSTATICS IN COMPUTER-AIDED DRUG DESIGN

TASK Quarterly, 1998
Hydrogen bonds and charge-charge interactions, determined by molecular electrostatics, play essential role in biopolymer-ligand associations. Accordingly, electrostatics is crucial in the qualitative and quantitative characterisation of the binding of ...
GABOR NARAY-SZABO, PETER MATYUS
doaj  

THE ALTERNATIVE DPP4 INHIBITORS FROM Coffea liberica BREW AND SPENT GROUNDS: IN VITRO STUDY AND LC-HRMS-BASED METABOLITES IDENTIFICATION

Bulletin of Pharmaceutical Sciences. Assiut University
Type 2 diabetes mellitus (T2DM) is still considerably a main health problem worldwide, especially in several developing countries. Natural products and bioactive metabolites have been widely investigated as alternative inhibitors of dipeptidyl peptidase ...
Florentinus Riswanto, Rio Chandra, Stephanus Waskitha, Enade Istyastono   +3 more
doaj   +1 more source

Progress in Computer-Aided Drug Design

, 2016
<p> <span style="font-family:'Times New Roman';font-size:11.0000pt;">Drug design, sometimes referred to as&nbsp;rational drug design&nbsp;or simply&nbsp;rational design, is the&nbsp;inventive&nbsp;process of finding new ...
Fidele Ntie-Kang, Misagh Naderi, William R. Pitt, Xia Wang, Federico Andreoli, Agnieszka A. Kaczor   +5 more
core   +1 more source

The Effect of Using Computer Technology Tools to Enhance the Teaching-Learning Process in CAD-CAM-CNC Module in Mechanical Engineering Subject Area [PDF]

, 2010
This study presents the evaluation of Computer Assisted Learning (CAL) package included in the teaching and learning methodology of computer aided design- computer aided design - computer numerical control (CAD-CAM-CNC) module.
Abdulrasool, Salah Mahdi, Khalaf, Haifa, Al Seddiqi, Mohamed, Mishra, Rakesh   +3 more
core   +1 more source