Results 51 to 60 of about 424,101 (310)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

THE APPLICATION OF COMBINATORIAL-VARIATIONAL APPROACH TO COMPUTER GEOMETRICAL MODELING OF ENGINEERING CONSTRUCTIONS AND BUILDINGS

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2013
The paper considers some issues of combinatorial-variational geometric modeling for computer-aided formation of engineering constructions and buildings in their design using modern computer-aided approach.
Vladimir VLADIMIROVICh Vanin   +2 more
doaj  

A two-stage multi-scale attention-based network for weakly supervised cataract fundus image enhancement

open access: yesScientific Reports
Cataract is a major cause of vision loss and hinders further diagnosis. However, enhancing cataract fundus images remains challenging due to limited paired cataract retinal images and the difficulty of recovering fine details in the retinal images.
Xiaoyong Fang   +4 more
doaj   +1 more source

Energy Integration and WEP Technical Evaluation of a Large-Scale PVC Production Process

open access: yesSci
PVC has become an indispensable material worldwide. However, its production method (suspension) presents significant sustainability challenges, such as negative environmental impacts and high operational costs due to energy consumption.
Antonio Mendivil-Arrieta   +4 more
doaj   +1 more source

Research regarding reverse engineering for aircraft components

open access: yesMATEC Web of Conferences, 2017
Reverse engineering is a useful technique used in manufacturing and design process of new components. In aerospace industry new components can be developed, based on existing components without technical Computer Aided Design (CAD) data, in order to ...
Udroiu Razvan
doaj   +1 more source

Aplicación de metadatos Dublin Core a los principales módulos CAD de CATIA V5 [PDF]

open access: yes, 2009
CATIA, Computer Aided Three-dimensional Interactive Application, is one of the most important commercial software used for Computer Aided Design (CAD), Computer Aided Engineering (CAE), and Computer Aided Manufacturing (CAM) in the aerospace and ...
Martinez-Avila, Daniel
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effect of the foam embellishments on the pedestrian safety of the vehicle front protection systems [PDF]

open access: yes, 2013
Pedestrian safety related compliance requirements are very important in case of design and development of the vehicle front protection systems. Computer aided engineering impact simulations were carried out to evaluate Head Injury Criterion (HIC) of a ...
Epaarachchi, J. A.   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A multidisciplinary and collaborative problem solving architecture for high-level computer aided process planning in discrete manufacturing [PDF]

open access: yes, 2007
Student Number : 0111474R - PhD thesis - School of Mechanical, Industrial and Aeronautical Engineering - Faculty of Engineering and the Built EnvironmentOne of the most daunting challenges in Computer Integrated Manufacturing (CIM) is bridging the ...
Botef, Ionel
core  

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