Results 91 to 100 of about 145,245 (295)
My thesis, entitled 'Transformative Mappings: the cartographer's house in the ecologist's garden', part design and part text, is concerned with contemporary design theory.
Ian Weir
doaj
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
An intelligent computer-aided design system incorporating considerations for aesthetics and the environment [PDF]
Amidst intense competition, manufacturers are constantly striving to improve their competence with others. In this respect, aesthetics of the product has become one of the prime factors in capturing market share.
Harunur Rashid, Abu Raihan Md.
core
The Sensitivity of State Differential Game Vessel Traffic Model
The paper presents the application of the theory of deterministic sensitivity control systems for sensitivity analysis implemented to game control systems of moving objects, such as ships, airplanes and cars.
Lisowski Józef
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Computer aided research method on the basis of general theory of root trajectories is considered in the frame of study of multi-channel control systems with varying parameters included as cofactors with arbitrary exponents in coefficients of the ...
V. V. Tkachenko
doaj
Encoding Theory of Mind in Character Design for Pedagogical Interactive Narrative
Computer aided interactive narrative allows people to participate actively in a dynamically unfolding story, by playing a character or by exerting directorial control.
Mei Si, Stacy C. Marsella
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source

