Results 111 to 120 of about 145,245 (295)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Preface [Computer Aided Systems Theory – EUROCAST 2024]

viv0,606Q210,
Quesada-Arencibia, Alexis, Moreno-Díaz, Roberto, Affenzeller, Michael   +2 more
core   +1 more source

Automating control system design via a multiobjective evolutionary algorithm [PDF]

, 2005
This chapter presents a performance-prioritized computer aided control system design (CACSD) methodology using a multi-objective evolutionary algorithm. The evolutionary CACSD approach unifies different control laws in both the time and frequency domains
Li, Y., Tan, K.C.
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Narrative support for technical documents: Formalising Rhetorical Structure Theory

, 2005
Business Process Re-engineering (BPR) is an area that requires a lot of technical documents and an important feature of a well-written document is a coherent narrative.
Peter Henderson, Henderson, Peter, Nishadi De Silva, De Silva, Nishadi   +3 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Determinación de la estructura molecular de geles mediante cálculos computacionales

Boletín de la Sociedad Española de Cerámica y Vidrio, 2004
This work constitutes a study guided to the design of the molecular geometry of ZrO2 gels aided by computer-based calculations (Density- Functional Theory).
Díaz-Díez, M. A., Macías-García, A., Silvero, G., Gordillo, R., Caruso, R.   +4 more
doaj  

Concept for Parameter Design and Optimization of Surface Acoustic Wave Devices

Известия высших учебных заведений России: Радиоэлектроника
Introduction. Bandpass filters on surface acoustic waves (SAW) are important components in frequency selection devices for receiving and transmitting electronic equipment.
A. S. Koigerov, A. V. Korlyakov
doaj   +1 more source