Results 121 to 130 of about 330,950 (237)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Scalp acupuncture and computer assisted cognitive rehabilitation for stroke: A meta-analysis of randomised controlled trials [PDF]
, 2023 Jiaqiang Xiao +3 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
A computer-assisted navigation technique for complex primary knee arthroplasty with intra-articular bone defect and instability: A case report and literature review [PDF]
, 2021 Norawee Wainipitapong
openalex +1 more source
Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source
Ultra Wideband Real-Time Locating System for Tracking People and Devices in the Operating Room
Current Directions in Biomedical Engineering, 2022 McGlone Simon A. +3 more
doaj +1 more source
Scientific ReportsHyperspectral imaging (HSI) has shown significant diagnostic potential for both intra- and postoperative perfusion assessment. The purpose of this study was to combine machine learning and neural networks with HSI to develop a method for detecting flap ...
Marianne Maktabi +3 more
doaj +1 more source
Development and application of operational techniques for the inventory and monitoring of resources and uses for the Texas coastal zone [PDF]
The author has identified the following significant results. Four LANDSAT scenes were analyzed for the Harbor Island area test sites to produce land cover and land use maps using both image interpretation and computer-assisted techniques.
Finley, R. +6 more
core +1 more source