Results 121 to 130 of about 550,093 (335)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

RFCs, MOOs, LMSs: Assorted Educational Devices\ud [PDF]

open access: yes, 2004
This paper discusses implicit social consequences of four basic internet protocols. The results are then related to the field of computer-assisted teaching.
Hrachovec, Herbert
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

System/360 Computer Assisted Network Scheduling (CANS) System [PDF]

open access: yes, 1972
Computer assisted scheduling techniques that produce conflict-free and efficient schedules have been developed and implemented to meet needs of the Manned Space Flight Network.
Brewer, A. C.
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Automatic depth scanning system for 3D infrared thermography

open access: yesCurrent Directions in Biomedical Engineering, 2016
Infrared thermography can be used as a pre-, intra- and post-operative imaging technique during medical treatment of patients. Modern infrared thermal cameras are capable of acquiring images with a high sensitivity of 10 mK and beyond.
Unger Michael   +2 more
doaj   +1 more source

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