Results 81 to 90 of about 4,605,719 (377)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Accuracy measurement of HoloLens2 IMUs in medical environments

open access: yesCurrent Directions in Biomedical Engineering, 2021
As augmented reality devices become more available, collaborative work in the augmented space is expected to increase. Knowing the position of participants allows for realistic interaction rather than passive participation.
Matyash Ivan   +3 more
doaj   +1 more source

The measurement of enhancement in mathematical abilities as a result of joint cognitive trainings in numerical and visual-spatial skills: A preliminary study [PDF]

open access: yes, 2015
A body of literature shows the significant role of visual-spatial skills played in the improvement of mathematical skills in the primary school. The main goal of the current study was to investigate the impact of a combined visuo-spatial and mathematical
Agus M   +5 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Integration Models for SDC-capable Medical Devices into an Existing OR Network

open access: yesCurrent Directions in Biomedical Engineering
The interconnection of medical devices in an operating room (OR) represents a major step in optimizing clinical processes and increasing the quality of treatment.
Deutschle Jennifer   +5 more
doaj   +1 more source

Acoustic Field Characterization of Medical Array Transducers Based on Unfocused Transmits and Single-Plane Hydrophone Measurements

open access: yesSensors, 2019
Medical ultrasonic arrays are typically characterized in controlled water baths using measurements by a hydrophone, which can be translated with a positioning stage.
Torben Marhenke   +5 more
doaj   +1 more source

Complex Care Management Program Overview - Technology [PDF]

open access: yes, 2013
This report provides an overview of technology based complex care management programs, including:Cook County Health and Hospitals System - Computer Assisted Quality of Life and Symptom Assessment of Complex PatientsUniversity of Missouri ...

core  

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

Stability and sensitivity of Learning Analytics based prediction models [PDF]

open access: yes, 2015
Learning analytics seek to enhance the learning processes through systematic measurements of learning related data and to provide informative feedback to learners and educators.
Giesbers, B.   +2 more
core   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

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