Results 111 to 120 of about 109,951 (299)
, 2009 Team training should reflect the increasing complexity of decision-making environments. Guidelines for scenario-based training were adopted for a distributed setting and tested in a pilot training session with a distributed team in the offshore oil ...
Kristina Lauche +8 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Comparison of the ABC/2 formula with computer-assisted volumetry of ischemic cerebellar stroke.
PLoS ONEIntroductionCurrent guidelines suggest surgical decompression for ischemic cerebellar stroke in case of significant mass effect. Recent research has aimed to identify a possible threshold for mass effect.
Milos Arsenovic +11 more
doaj +1 more source
Decision Making in Mobile Telemedicine Complex
Research is dedicated to computer-based decisionmaking technology intended for screening diagnostics and its basic principle implementation in the Mobile Telemedicine Screening Complex (MTSC).
Markovičs, Zigurds
core
, 2008 Empirical studies of cognitive representations have shown that judgment and reasoning can be affected by the spatial properties of information. Empirical studies of human-computer interface design have shown that spatial presentations of information can ...
Doctor Of Philosophy +2 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Digital Health Technology & Cancer Care: Conceptual Framework Leading Comprehensive Fruitfulness
Journal of Healthcare LeadershipSunil Jain,1,* Prem Kamal Jain,2,* Ashok Kumar Puranik3,4,* 1Armed Forces Medical Services, India; 2Department of Computational Biology, Indraprastha Institute of Information Technology, New Delhi, India; 3AIIMS, Guwahati, India; 4Alfred ...
Jain S, Jain PK, Puranik AK
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Educación MédicaResumen: Introducción: la satisfacción académica de los estudiantes de Medicina puede verse afectada por las expectativas y proyecciones emocionales preconcebidas acerca de la carrera.
Alberto Guevara Tirado
doaj +1 more source
Information quality assessment and effects on inventory decision-making [PDF]
, 2009 Information quality has become a critical concern to the success of organisations. Numerous business initiatives have been delayed or even cancelled, citing poor-quality information as the main reason.
Ge, Mouzhi
core