Results 101 to 110 of about 109,951 (299)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Effect of the Number of Clinical Bracket Points on the Accuracy of Curve Fitted to Dental Arch Form by 3D Method

Journal of Islamic Dental Association of Iran, 2012
Background and Aim : Adjustment of an accurate curve to the dental arch is an important part of orthodontic treatment. Our goal was comparing the fitting accuracy of two curves constructed by different numbers of clinical bracket points (CBP) to the ...
Mahtab Nouri, Arash Farzan, Mohammad reza Safavi, Ali reza Akbarzadeh Baghban   +3 more
doaj  

How and Why Decision Models Influence Marketing Resource Allocations

We study how and why model-based Decision Support Systems (DSSs) influence managerial decision making, in the context of marketing budgeting and resource allocation.
Rangaswamy, A., Lilien, G.L., Starke, K., Bruggen, G.H. van   +3 more
core  

Computer assisted modelling of linear, integer and separable programming problems

, 1984
For mathematical programming (MP) to have greater impact upon the decision making process, MP software systems must offer suitable support in terms of model communication and modelling techniques .
Mitra, G, Darby-Dowman, K, Lucas, CA
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A multi-criteria decision making approach for food engineering

, 2011
The objective of this study was to propose a decision making approach and tools (software packages) to solve the multi-criteria decision making problems arising in the food engineering.
Abakarov, Alik
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Impact of computer-based treatment planning software on clinical judgment of dental students for planning prosthodontic rehabilitation

Advances in Medical Education and Practice, 2014
Saee Deshpande, Jayashree Chahande Department of Prosthodontics, Vidya Shikshan Prasarak Mandal's (VPSM) Dental College and Research Centre, Nagpur, Maharashtra, India Purpose: Successful prosthodontic rehabilitation involves making many ...
Deshpande S, Chahande J
doaj  

Oral mucosal lesions triage via YOLOv7 models

Journal of the Formosan Medical Association
Background/purpose: The global incidence of lip and oral cavity cancer continues to rise, necessitating improved early detection methods. This study leverages the capabilities of computer vision and deep learning to enhance the early detection and ...
Yu Hsu, Cheng-Ying Chou, Yu-Cheng Huang, Yu-Chieh Liu, Yong-Long Lin, Zi-Ping Zhong, Jun-Kai Liao, Jun-Ching Lee, Hsin-Yu Chen, Jang-Jaer Lee, Shyh-Jye Chen   +10 more
doaj   +1 more source