Results 111 to 120 of about 149 (148)
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino+12 more
wiley +1 more source
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri+7 more
wiley +1 more source
In this randomized clinical trial conducted among 142 community‐dwelling older adults at high risk for falls over 12 months, a Dalcroze Eurhythmics exercise intervention (once weekly, group‐based) improved a variety of physical and cognitive/executive function outcomes compared with a multicomponent exercise intervention (twice weekly, group‐ and home ...
Mélany Hars+7 more
wiley +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Skeletal muscle analysis with the aid of a computer-assisted image analysing process.
M P, du Plessis, H N, Louw, H J, Geyer
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Computer Assistance Image Processing Spores Counting
2009 International Asia Conference on Informatics in Control, Automation and Robotics, 2009To monitor plant disease which caused by spores, it is needed to obtain the spores image exterior outline characteristic, prepares for spores type analysis and automatic counting. This paper uses computer assistance digital image processing, realized image pretreatment, determined the threshold value reasonably, and transformed the gray image to binary
Jigang Li, Pengyun Xu
openaire +2 more sources
Image processing techniques in computer-assisted patch clamping
SPIE Proceedings, 2010Patch clamping is used in electrophysiology to study single or multiple ion channels in cells. Multiple micropipettes are used as electrodes to collect data from several cells. Placement of these electrodes is a time consuming and complicated task due to the lack of depth perception, limited view through the microscope lens and the possibility of ...
Mahdi Azizian+5 more
openaire +2 more sources