Results 41 to 50 of about 45,210 (305)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Library Instruction for Freshman English: A Multi-Year Assessment of Student Learning
Evidence Based Library and Information Practice, 2011 Objective – The objective of this study was twofold: 1) to assess the effectiveness of curriculum changes made from the 2009 freshman English library instruction curriculum to the 2010 curriculum at Loyola Marymount University (LMU); and 2) to evaluate ...
Susan Gardner Archambault
doaj +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Replacement of traditional lectures with computer‐based tutorials: A case study [PDF]
, 1996 A set of computer‐based tutorial files were produced in‐house and used to replace two traditional lectures. Students submitted feedback on their use of the CAL material.
Lavelle, Derek, Derek Lavelle
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Evidence Based Library and Information Practice, 2006 Objective –To demonstrate the effectiveness of interactive multimedia tutorials in delivering library educational content, and to evaluate librarian experiences of developing multimedia tutorials, both aspart of the LUMENS (Drabenstott) project.Design ...
David Herron, Lotta Haglund
doaj
MATEC Web of Conferences, 2017 Transdisciplinary interest and preoccupations regarding computer-assisted instruction have stirred our urge to perform a thorough study of the field and trends as well as to uphold certain approaches that have emerged in specialized scientific research ...
Konnerth Sara, Lobin Gunter
doaj +1 more source
Examining Pre-Service Mathematics Teachers’ Attitudes Towards Computer Assisted Education
Kuramsal Eğitimbilim Dergisi, 2014 Nowadays, the use of computers involves in our lives more with the developing technology. Facilitating the work of people, computers provide convenience in the field of education as in every other field.
Betül KÜÇÜK +3 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source