From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Communicative approaches in computer-assisted language instruction (CALl)
Per Linguam : A Journal of Language Learning, 2013 This article maintains that software for computer-assisted language instruction is largely dominated by audio-lingual approaches, with their emphasis on drill-andpractice, structural drill and manipulation of discrete items.
Jannie Botha
doaj +1 more source
Computer-assisted instruction [PDF]
, 1974 The results are presented of a project of research and development on strategies for optimizing the instructional process, and dissemination of information about the applications of such research to the instructional medium of computer-assisted ...
Atkinson, R. C.
core
The information flow of the Computer Assisted Instruction.
, 2015 The information flow of the Computer Assisted Instruction.
Laura García de Diego (739806) +2 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Computer-based programs on acquisition of reading skills in schoolchildren (review of contemporary foreign investigations) [PDF]
Современная зарубежная психология, 2015 The article presents a description of 17 computer-based programs, which were used over the last 5 years (2008—2013) in 15 studies of computer-assisted reading instruction and intervention of schoolchildren.
Prikhoda N.A.
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The Effectiveness of Computer-Assisted Instruction in Developmental Mathematics [PDF]
, 2010 This quasiexperimental study compared academic performance of students enrolled in a developmental mathematics course using traditional instruction (i.e., lecture) and traditional instruction supplemented with computer-assisted instruction.
Spradlin, Kathy Dye, Ackerman, Beth
core +1 more source
Library Instruction for Freshman English: A Multi-Year Assessment of Student Learning
Evidence Based Library and Information Practice, 2011 Objective – The objective of this study was twofold: 1) to assess the effectiveness of curriculum changes made from the 2009 freshman English library instruction curriculum to the 2010 curriculum at Loyola Marymount University (LMU); and 2) to evaluate ...
Susan Gardner Archambault
doaj +3 more sources