Results 71 to 80 of about 4,029,964 (283)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Teaching machine translation and translation technology: a contrastive study [PDF]

, 2001
The Machine Translation course at Dublin City University is taught to undergraduate students in Applied Computational Linguistics, while Computer-Assisted Translation is taught on two translator-training programmes, one undergraduate and one ...
Way, Andy, Kenny, Dorothy
core   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Information processing in computer-assisted interventions: 4th international conference, 2013 [PDF]

, 2014
Information processing in computer-assisted interventions: 4th international conference ...
Barratt, Dean, Jannin, Pierre, Fichtinger, Gabor, Cotin, Stéphane, Pierre Jannin, Jannin, P, Dean Barratt, Barratt, D, Fichtinger, G, Gabor Fichtinger, Cotin, S, Stephane Cotin   +11 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Online learning approaches in Computer Assisted Translation [PDF]

, 2013
We present a novel online learning approach for statistical machine translation tailored to the computer assisted translation scenario. With the introduction of a simple online feature, we are able to adapt the translation model on the fly to the ...
Cettolo, Mauro, Federico, Marcello, Prashant M.   +2 more
core  

Computer‐assisted learning as an alternative to didactic lectures: A study of teaching the physics of diagnostic imaging [PDF]

, 1999
A computer‐assisted learning (CAL) package entitled Physics of Diagnostic Imaging was developed in 1995 to replace five hours of didactic lectures at the University of Glasgow Faculty of Veterinary Medicine, and has been available as an additional ...
Dale, V.H.M., V.H. M. Dale, Irvine, D.R., D.R. Irvine, M. Sullivan, V.H.M. Dale, Sullivan, M., D. R. Irvine   +7 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Of Dragons and Speech Recognition Wizards and Apprentices

Revista Tradumàtica, 2014
Despite being used by a minority of professional translators, Automatic Speech Recognition (ASR) systems do have a lot of potential for effective integration into professional workflows.
Dragos Ciobanu
doaj   +1 more source

Computer-assisted translation systems [PDF]

Proceedings of the first conference on Applied natural language processing -, 1983
The standard design for a computer-assisted translation system consists of data entry of source text, machine translation, and revision of raw machine translation. This paper discusses this standard design and presents an alternative multi-level design consisting of integrated word processing, terminology aids, preprocessing aids and a link to an off ...
openaire   +1 more source