Results 121 to 130 of about 1,878,180 (248)

Explication of screen culture

Arte y Sociedad
The screen is rapidly becoming the dominant mode of modern culture, acting as a technological tool, a medium and a special, in its own way unique environment for the multidimensional human existence.
Dmitry Belyaev, Ksenia Aksenova
doaj  

Health Professionals' Readiness and Its Associated Factors to Implement Telemedicine System at Public Hospitals in Harari Region, Eastern Ethiopia, 2024: A Cross-Sectional Study. [PDF]

Health Sci Rep
Hailu S, Negash B, Kassaye D, Ahmed N, Yeshitila M, Mezmur H.   +5 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Retraction Note: Plant disease recognition using residual convolutional enlightened Swin transformer networks. [PDF]

Sci Rep
Kalpana P, Anandan R, Hussien AG, Migdady H, Abualigah L.   +4 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Television and computer use and dementia risk in older adults with limited leisure or social activities: A prospective cohort study. [PDF]

Alzheimers Dement
Li J, Xue H, Leng Y, Samus QM, Nowrangi M, Szanton SL, Xue QL, Li J.   +7 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Electronic Medical Record Attitudes and Predictors of Adoption Among Ethiopian Health Professionals: Cross-Sectional Study. [PDF]

JMIR Form Res
Abebe MA, Urgie BM, Lema GD, Yimam MA, Abosetugn AE, Dejene TM, Kebede AA, Gebreegziabher ZA, Feleke AK, Abebe DA, Amin HM, Mingude AB, Sherif ZA.   +12 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gaming disorder: Prevalence and association with psychosocial outcomes in the German general adult population. [PDF]

Addict Behav Rep
Hajek A, Stickley A, Peltzer K, Pengpid S, König HH.   +4 more
europepmc   +1 more source