Results 81 to 90 of about 21,987 (211)

The Effect of Using Computer Technology Tools to Enhance the Teaching-Learning Process in CAD-CAM-CNC Module in Mechanical Engineering Subject Area

open access: yes, 2010
This study presents the evaluation of Computer Assisted Learning (CAL) package included in the teaching and learning methodology of computer aided design- computer aided design - computer numerical control (CAD-CAM-CNC) module.
Abdulrasool, Salah Mahdi   +3 more
core  

Computer Aided Process Engineering for Sustainability Analysis of Food Production

open access: yesChemical Engineering Transactions, 2015
We propose a dedicated tool that permits the evaluation of food production process sustainability, in particular virgin olive oil process. It is based on an integrated process-product-enterprise (P²E) approach that allows systematically taking into ...
G. Busset   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Repairing triangle meshes built from scanned point cloud [PDF]

open access: yes, 2007
The Reverse Engineering process consists of a succession of operations that aim at creating a digital representation of a physical model. The reconstructed geometric model is often a triangle mesh built from a point cloud acquired with a scanner ...
PERNOT, Jean-Philippe   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

13th International Conference on Computer Aided Engineering

open access: yes, 2017
These proceedings of the 13th International Conference on Computer Aided Engineering present selected papers from the event, which was held in Polanica Zdrój, Poland, from June 22 to 25, 2016.
Rusiński, Eugeniusz, Pietrusiak, Damian
core   +1 more source

Dual modality prompt learning for visual question-grounded answering in robotic surgery

open access: yesVisual Computing for Industry, Biomedicine, and Art
With recent advancements in robotic surgery, notable strides have been made in visual question answering (VQA). Existing VQA systems typically generate textual answers to questions but fail to indicate the location of the relevant content within the ...
Yue Zhang   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

The concept of development of computer aided design programs for bridges or other engineering structures according to the specified criterion of optimality

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2019
In article on the basis of generalization of experience of creating in the period from 1997 to 2015 computer-aided design of various bridge structures by fifteen graduate students of the Department of Bridges and Transport Tunnels MADI (GTU) under the ...
Pavel M. Salamakhin   +1 more
doaj   +1 more source

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