Results 111 to 120 of about 260,987 (350)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A hardware-software architecture for computer vision systems

open access: yesITEGAM-JETIA, 2018
Computer vision systems are based on capture and processing of images, from which information for the application is extracted. This paper presents a hybrid platform which can be easily configured and efficiently used for a large number of applications ...
Antônio Otavio Fernandes   +3 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A NEW OS ARCHITECTURE FOR IOT

open access: yesБезопасность информационных технологий, 2018
Current computer operating systems architectures are not well suited for the coming world of connected objects, known as the Internet of Things (IoT) for multiple reasons: poor communication performances in both point-to-point and broadcast cases, poor ...
Jean Y. Astier   +3 more
doaj   +1 more source

An information-driven architecture for cognitive systems research

open access: yes, 2008
Wrede S. An information-driven architecture for cognitive systems research. Bielefeld (Germany): Bielefeld University; 2008.With computer science more and more leaving the traits of solitary algorithms and distinct disciplines towards complex intelligent
Wrede, Sebastian ; https://orcid.org/
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Hopes and facts in evaluating the performance of HPC-I/O on a cloud environment

open access: yesJournal of Computer Science and Technology, 2015
Currently, there is an increasing interest about the cloud platform by the High Performance Computing (HPC) community, and the Parallel I/O for High Performance Systems is not an exception.
Pilar Gómez Sánchez   +3 more
doaj  

Trends in computer system structure and architecture [PDF]

open access: yes, 1976
Management of Complexity is the overriding concern in the development of modern Data Processing Systems. We observe a split into systems which are used in a computing center, and systems which are used by an individual department. The first class of systems is characterized by general purpose attributes of its structure and features for adaption to a ...
openaire   +1 more source

Ar-CHI-tecture: Architecture and Interaction

open access: yes, 2012
The rise of ubiquitous computing leads to a natural convergence between the areas of architectural design (the design of buildings, spaces and experience of being in and moving through them) and HCI.
Mathew, Anijo   +16 more
core   +1 more source

Business process and software architecture model co-evolution patterns [PDF]

open access: yes, 2012
Software systems are subject to change. To embrace change, the systems should be equipped with automated mechanisms. Business process and software architecture models are two artifacts that are subject to change in an interrelated manner that requires ...
Pooyan Jamshidi (5276344)   +5 more
core   +1 more source

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