Results 21 to 30 of about 132,284 (292)

A Metaheuristic Search Algorithm Based on Sampling and Clustering

IEEE Access
As optimization problems become more complicated and extensive, parameterization becomes complex, resulting in a difficult task requiring significant amounts of time and resources.
Maria Harita, Alvaro Wong, Remo Suppi, Dolores Rexachs, Emilio Luque   +4 more
doaj   +1 more source

DiFLUsion: A new spatiotemporal early warning system for HPAI

International Journal of Infectious Diseases, 2022
Purpose: Highly pathogenic avian influenza (HPAI) represents a global threat due to the devastating economic losses for the poultry industry and a recognized zoonotic potential.
I. Iglesias, K. Kanankege, E.J. Valencia, C.J. Liu, C.E. Blanco, S. Lim, J.A. Gomez-Perez, C. Tomas-Tenllado, A. De la Torre, A. Perez   +9 more
doaj   +1 more source

Multilayered Autoscaling Performance Evaluation: Can Virtual Machines and Containers Co–Scale?

International Journal of Applied Mathematics and Computer Science, 2019
The wide adoption of cloud computing by businesses is due to several reasons, among which the elasticity of the cloud virtual infrastructure is the definite leader.
Podolskiy Vladimir, Jindal Anshul, Gerndt Michael   +2 more
doaj   +1 more source

Zone adaptive fuel mapping for high resolution wildfire spread forecasting

Scientific Reports
Extreme wildfire events (EWE), although a rare natural hazard, account for a substantial portion of global wildfire damage, requiring proactive anticipation and mitigation due to their increasing occurrence.
Paula Sánchez, Irene González, Carlos Carrillo, Ana Cortés, Remo Suppi, Tomàs Margalef   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

A Cerebellar Neuroprosthetic System: Computational Architecture and in vivo Test [PDF]

Frontiers in Bioengineering and Biotechnology, 2014
Emulating the input-output functions performed by a brain structure opens the possibility for developing neuroprosthetic systems that replace damaged neuronal circuits. Here, we demonstrate the feasibility of this approach by replacing the cerebellar circuit responsible for the acquisition and extinction of motor memories.
Herreros, Ivan, Giovannucci, Andrea, Taub, Aryeh H., Hogri, Roni, Magal, Ari, Bamford, Sim, Prueckl, Robert, Verschure, Paul F. M. J.   +7 more
openaire   +2 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

BTI Aging Influence Analysis and Mitigation in Flash ADCs

Chips
Bias Temperature Instability (BTI)-induced aging of transistors is a serious concern in modern electronic circuits, yet its effects on the operation of mixed-signal circuits have not been extensively studied.
Konstantina Mylona, Helen-Maria Dounavi, Yiorgos Tsiatouhas   +2 more
doaj   +1 more source