Results 111 to 120 of about 770,880 (300)
Applications Development for the Computational Grid [PDF]
The Computational Grid has promised a great deal in support of innovative applications, particularly in science and engineering. However, developing applications for this highly distributed, and often faulty, infrastructure can be demanding. Often it can take as long to set up a computational experiment as it does to execute it.
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Watershed management and hydrological modeling require data related to the very important matter of precipitation, often measured using raingages or weather stations.
Ly, S., Charles, C., Degré, A.
doaj
Enhancing Livestock Detection: An Efficient Model Based on YOLOv8
Maintaining a harmonious balance between grassland ecology and local economic development necessitates effective management of livestock resources. Traditional approaches have proven inefficient, highlighting an urgent need for intelligent solutions ...
Chengwu Fang +6 more
doaj +1 more source
COMPONENTS IMPACT ANALYZER WITH GENETIC ALGORITHM [PDF]
High quality software can be obtained by means of rigorous testing of all the components of the software. This research work has proposed an automated software testing framework that performs a mutant based components impact analysis to identify the ...
D. Jeyamala +3 more
doaj
Collaborative computing and applications [PDF]
Weiming Shen 0001 +2 more
openaire +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
S.22-24This report summarises the results of the 2002 ACM SIGGRAPH and Eurographics Campfire. The topic of this event is "Production Process of 3D Computer Graphics Applications - Structures, Roles and Tools".
Haller, M. +3 more
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