Results 101 to 110 of about 770,880 (300)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Exploring the Impact of Computer Applications on Cross-Border E-Commerce Performance

IEEE Access
In the dynamic landscape of global commerce, cross-border e-commerce has emerged as a critical avenue for businesses to expand their reach and capitalize on international markets.
Lijing Jin, Lin Chen
doaj   +1 more source

Elsevier's Journal of Network and Computer Applications

Managing Editor-in-Chief M. Atiquzzaman Journal Metrics Impact Factor: 2.331 5-Year Impact Factor: 2.485 Source Normalized Impact per Paper (SNIP): 2.762 SCImago Journal Rank (SJR): 1.100 The Journal of Network and Computer Applications ...
BONONI, LUCIANO
core  

Early Computer VS Modern Computer: A Comparitive Study and an Approach to Advance Computer

, 2012
In this paper, emphasis has been given on the gradual and continuous advancement of computer from on and before 300BC to 2012 and beyond. During this very long period of time, a simple device like computer has witnessed many significant changes in its ...
Dr. Zobair Ullah
core  

Computer-based laboratory for data communications and computer networking

, 2004
Data communications and computer networking (DCCN) has established itself as an essential part of most computer science and engineering curricula, usually in the form of courses and/or laboratories. For reliable training in this area, this study presents
Sharafeddine S., Kayssi, Ayman, Kayssi A., Karaki H., Sharafeddine, Sanaa, Karaki, Houda   +5 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Network Security Situational Awareness Based on Improved Particle Swarm Algorithm and Bidirectional Long Short-Term Memory Modeling

Applied Sciences
With the continuous development of information technology, network security risks are also rising, and the ability to quickly perceive network threats has become an important prerequisite and an important means to cope with network risks.
Peng Zheng, Yun Cheng, Wei Zhu, Bo Liu, Shuhong Liu, Shijie Wang, Jinyin Bai   +6 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source