Results 101 to 110 of about 1,373,407 (260)

A Study of Basic 3D Visualization Architecture for Network Operation and Management Tools [PDF]

open access: yes, 2018
Recently, network operation tools using 3D visualization technologies have become more and more important. Generally, 3D visualized network operation tools are useful for computer network management or operation.
Ogashiwa, Nobuo
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Highly parallel computer architecture for robotic computation [PDF]

open access: yes
In a computer having a large number of single instruction multiple data (SIMD) processors, each of the SIMD processors has two sets of three individual processor elements controlled by a master control unit and interconnected among a plurality of ...
Bejczy, Anta K., Fijany, Amir
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Research and implementation of network transmission situation awareness

open access: yesTongxin xuebao, 2010
The advanced ideas of situation awareness were introduced to network transmission and NTSA(network transmission situation awareness) model was established based on spatial traffic clustering.Around the key technologies of the model,situation factors were
ZHUO Ying, GONG Chun-ye, GONG Zheng-hu
doaj  

Computer Architecture for Industrial Training Evaluation

open access: yesApplied System Innovation
Companies have tried to innovate in their training processes to increase their productivity indicators, reduce equipment maintenance costs, and improve the work environment.
Luz E. Gutiérrez   +5 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Protocol of GIOP onto RapidIO——RIO-IOP

open access: yesTongxin xuebao, 2012
In embedded system application,all hardware elements based on bus mode.TCP/IP can not satisfy their communications,especially the interconnection of chips and boards.Therefore,in embedded environment,RapidIO interconnection framework is employed.There is
Wen-yu CHEN, Ru ZENG, Wei PI, Wen LI
doaj  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

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