Results 41 to 50 of about 214,421 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The architecture of the spherical sky building and its protective role for the Earth Mechanisms for maintaining the hermetic ceiling - the sky - in architecture

Journal of Architecture, Art & Humanistic Science
The sky constitutes an incubating element for the planet Earth that protects it from all the dangers that occur in cosmic space. It can be likened to an outer shell that surrounds the Earth, and it serves as a large envelope or protective ceiling for ...
Dr. Manal Ibrahim Adham Haj Yousef Lecturer at Architecture Department Theba Maadi Academy for Engineering and Computer Science
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

BTCP: Binary Temporal Convolutional Network-Based Data Prefetcher for Low Inference Latency and Storage Overhead

IEEE Access
Data prefetching is crucial for hiding long-latency memory access on modern high-performance processors. Machine learning (ML)-based data prefetchers have demonstrated superior address prediction performance compared with traditional rule-based ...
Chang Ho Ryu, Tae Hee Han
doaj   +1 more source

Development Status and Trends of Space Processor

天地一体化信息网络, 2023
Space electronic system is the ＆quot;brain＆quot; of aerospace engineering models and the core fi eld of competitive development of major countries around the world.As the most core device in space electronic system, space processor directly aff ects the ...
Zhigang YU, Xu FENG, Zhou LU, Jixing GAO, Wenhui DING   +4 more
doaj  

Formulation and Implementation of Frequency-Dependent Linear Response Properties with Relativistic Coupled Cluster Theory for GPU-accelerated Computer Architectures [PDF]

, 2023
Xiang Yuan, Loïc Halbert, Johann Valentin Pototschnig, Anastasios Papadopoulos, Sonia Coriani, Lucas Visscher, André Severo Pereira Gomes   +6 more
openalex   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A Detailed Study of SOT-MRAM as an Alternative to DRAM Primary Memory in Multi-Core Environment

IEEE Access
As the current primary memory technology is reaching its limits, it is essential to explore alternative memory technologies to accommodate modern applications and use cases.
H. D. Kallinatha, Sadhana Rai, Basavaraj Talawar   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Study on Improvement of Blockchain Application to Overcome Vulnerability of IoT Multiplatform Security

Energies, 2019
IoT devices are widely used in the smart home, automobile, and aerospace areas. Note, however, that recent information on thefts and hacking have given rise to many problems.
Seong-Kyu Kim, Ung-Mo Kim, Jun-Ho Huh
doaj   +1 more source