Results 31 to 40 of about 214,421 (299)

ALCEA: The Architecture Life-Cycle Effect Analysis Method

open access: yesIEEE Open Journal of Systems Engineering
This article describes the architecture life cycle effect analysis (ALCEA) method, a structured method for evaluating proposed new architectures for software-intensive systems. The method evaluates a proposed architecture by quantifying its effect on the
Jakob Axelsson   +6 more
doaj   +1 more source

An Area Efficient Composed CORDIC Architecture

open access: yesAdvances in Electrical and Computer Engineering, 2014
This article presents a composed architecture for the CORDIC algorithm. CORDIC is a widely used technique to calculate basic trigonometric functions using only additions and shifts.
AGUIRRE-RAMOS, F.   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Event‐based high throughput computing: A series of case studies on a massively parallel softcore machine

open access: yesIET Computers & Digital Techniques, 2023
This paper introduces an event‐based computing paradigm, where workers only perform computation in response to external stimuli (events). This approach is best employed on hardware with many thousands of smaller compute cores with a fast, low‐latency ...
Mark Vousden   +7 more
doaj   +1 more source

Identification of Return-Oriented Programming Attacks Using RISC-V Instruction Trace Data

open access: yesIEEE Access, 2022
An increasing number of embedded systems include dedicated neural hardware. To benefit from this specialized hardware, deep learning techniques to discover malware on embedded systems are needed. This effort evaluated candidate machine learning detection
Daniel F. Koranek   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An integrated taxonomy of standard indicators for ranking and selecting supercomputers

open access: yesIET Computers & Digital Techniques, 2023
Due to the ever‐increasing computing requirements of modern applications, supercomputers are at the centre of attraction as a platform for high‐performance computing.
Davood Maleki   +2 more
doaj   +1 more source

Energy-Efficient Shared Cache Using Way Prediction Based on Way Access Dominance Detection

open access: yesIEEE Access, 2021
To meet the performance demands of chip multiprocessors, chip designers have increased the capacity and hierarchy of cache memories. Accordingly, a shared lower-level cache reduces conflict misses by adopting a multi-way set-associative structure with ...
Yun-Seok Oh, Eui-Young Chung
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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