Results 61 to 70 of about 1,373,407 (260)
A Detailed Study of SOT-MRAM as an Alternative to DRAM Primary Memory in Multi-Core Environment
As the current primary memory technology is reaching its limits, it is essential to explore alternative memory technologies to accommodate modern applications and use cases.
H. D. Kallinatha +2 more
doaj +1 more source
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
IoT devices are widely used in the smart home, automobile, and aerospace areas. Note, however, that recent information on thefts and hacking have given rise to many problems.
Seong-Kyu Kim, Ung-Mo Kim, Jun-Ho Huh
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
RASP ABSTRACT MACHINE EMULATOR – EXTENDING THE EMUSTUDIO PLATFORM [PDF]
This paper presents the RASP (Random Access Stored Program) abstract machine emulator implemented as a plugin for emuStudio – extendable platform for computer architectures emulation.
Michal ŠIPOŠ, Slavomír ŠIMOŇÁK
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Fault tolerant hypercube computer system architecture [PDF]
A fault-tolerant multiprocessor computer system of the hypercube type comprising a hierarchy of computers of like kind which can be functionally substituted for one another as necessary is disclosed.
Chow, Edward, Madan, Herb S.
core +1 more source
Addressing Mode Extension to the ARM/Thumb Architecture
In this paper, two new addressing modes are introduced to the 16-bit Thumb instruction set architecture to improve performance of the ARM/Thumb processors.
KIM, D.-H.
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Silicon CMOS architecture for a spin-based quantum computer
Recent advances in quantum error correction (QEC) codes for fault-tolerant quantum computing \cite{Terhal2015} and physical realizations of high-fidelity qubits in a broad range of platforms \cite{Kok2007, Brown2011, Barends2014, Waldherr2014, Dolde2014,
Dzurak, A. S. +3 more
core +2 more sources

