Results 61 to 70 of about 1,969,838 (357)
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez+3 more
wiley +1 more source
Interconnection Networks for Scalable Quantum Computers [PDF]
We show that the problem of communication in a quantum computer reduces to constructing reliable quantum channels by distributing high-fidelity EPR pairs. We develop analytical models of the latency, bandwidth, error rate and resource utilization of such
Isailovic, Nemanja+3 more
core +3 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
A Study of Basic 3D Visualization Architecture for Network Operation and Management Tools [PDF]
Recently, network operation tools using 3D visualization technologies have become more and more important. Generally, 3D visualized network operation tools are useful for computer network management or operation.
Ogashiwa, Nobuo
core
BRISC-V emulator: a standalone, installation-free, browser-based teaching tool [PDF]
Many computer organization and computer architecture classes have recently started adopting the RISC-V architecture as an alternative to proprietary RISC ISAs and architectures.
Isakov, Mihailo, Kinsy, Michel A.
core
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
An Area Efficient Composed CORDIC Architecture
This article presents a composed architecture for the CORDIC algorithm. CORDIC is a widely used technique to calculate basic trigonometric functions using only additions and shifts.
AGUIRRE-RAMOS, F.+3 more
doaj +1 more source
Techniques for improving reliability of computers [PDF]
Modular design techniques improve methods of error detection, diagnosis, and recovery. Theoretical computer (MARCS (Modular Architecture for Reliable Computer Systems)) study deals with postulated and modeled technology indigenous to 1975-1980.
Bouricius, W. G.+5 more
core +1 more source
Neural Networks Architecture Evaluation in a Quantum Computer
In this work, we propose a quantum algorithm to evaluate neural networks architectures named Quantum Neural Network Architecture Evaluation (QNNAE). The proposed algorithm is based on a quantum associative memory and the learning algorithm for artificial
da Silva, Adenilton José+1 more
core +1 more source
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source