Results 71 to 80 of about 300,740 (315)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Addressing Mode Extension to the ARM/Thumb Architecture
Advances in Electrical and Computer Engineering, 2014 In this paper, two new addressing modes are introduced to the 16-bit Thumb instruction set architecture to improve performance of the ARM/Thumb processors.
KIM, D.-H.
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Classification of Scripting Systems for Entertainment and Serious Computer Games [PDF]
, 2011 The technology base for modern computer games is usually provided by a game engine. Many game engines have built-in dedicated scripting languages that allow the development of complete games that are built using those engines, as well as extensive ...
Anderson, Eike F., Eike Falk Anderson
core +1 more source
Sensors, 2018 In the Republic of Korea, one of the most widely discussed subjects related to future logistics technology is the drone-based delivery (transportation) system. Much (around 75%) of Korea’s territory consists of mountainous areas; however, the costs
Jun-Ho Huh
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Mechanisms for Parallelism Specialization for the DySER Architecture [PDF]
, 2012 Specialization is a promising direction for improving processor energy efficiency. With functionality specialization, hardware is designed for application-specific units of computation.
Ho, Chen-Han +3 more
core +1 more source
Intelligent architecture for automatic resource allocation in computer clusters [PDF]
, 2003 As the need for more reporting and assessment of information increase exponentially, computer-based applications consume resources at an alarmingly rapid rate.
Getov, Vladimir +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Choice architecture and design with intent [PDF]
, 2009 Motivation – Choice architecture (Thaler & Sunstein, 2008) is a phrase of the moment among politicians and economists seeking to influence public behaviour, but the relevance of the concept to designers has received little attention.
Dan Lockton +8 more
core +1 more source