Results 71 to 80 of about 4,598,340 (299)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
LARC 5350 Landscape Architecture Computer Applications 2011, Professor John Fain.
, 2011 Selected student work from the 2011 landscape architecture course LARC 5350 Landscape Architecture Computer Applications, Professor John Fain. Student work includes: Craig Ranch Sundial, McKinney, Texas, Traci Church; Craig Ranch Sun Dial, McKinney ...
Landscape Architecture Program
core +1 more source
A Detailed Study of SOT-MRAM as an Alternative to DRAM Primary Memory in Multi-Core Environment
IEEE AccessAs the current primary memory technology is reaching its limits, it is essential to explore alternative memory technologies to accommodate modern applications and use cases.
H. D. Kallinatha +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Energies, 2019 IoT devices are widely used in the smart home, automobile, and aerospace areas. Note, however, that recent information on thefts and hacking have given rise to many problems.
Seong-Kyu Kim, Ung-Mo Kim, Jun-Ho Huh
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Do (and say) as I say: Linguistic adaptation in human-computer dialogs [PDF]
, 2014 © Theodora Koulouri, Stanislao Lauria, and Robert D. Macredie. This article has been made available through the Brunel Open Access Publishing Fund.There is strong research evidence showing that people naturally align to each other’s vocabulary, sentence ...
Macredie, R, Kolouri, T, Lauria, S
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Addressing Mode Extension to the ARM/Thumb Architecture
Advances in Electrical and Computer Engineering, 2014 In this paper, two new addressing modes are introduced to the 16-bit Thumb instruction set architecture to improve performance of the ARM/Thumb processors.
KIM, D.-H.
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source