Results 121 to 130 of about 266,906 (297)

Analyzing the effects of computer-assisted dynamic assessment on L2 writing tasks for Chinese learners

open access: yesCogent Education
This study investigates the effects of computer-assisted Interventionist Dynamic Assessment (IDA) and Hybrid Dynamic Assessment (HDA) on the organizational skills of L2 writing among Chinese university students, addressing gaps in traditional product ...
Sun Wei, Yousun Shin
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

PERANCANGAN APLIKASI PEMBELAJARAN ORKESTRA GAMELAN SECARA MANDIRI BERBASIS COMPUTER ASSISTED INSTRUCTION

open access: yesTechno.Com, 2013
Terdapat berbagai kendala dalam menyelenggarakan musik orkestra, karena karakteristiknya yang memerlukan pemenuhan syarat tersendiri dalam hal sarana dan prasarana, seperti memerlukan ruang yang luas, instrumen yang banyak, tim pemain, dan biaya yang ...
Achmad Wahid Kurniawan   +1 more
doaj  

Computer-assisted instruction before colonoscopy is as effective as nurse counselling, a clinical pilot trial. [PDF]

open access: yesEndosc Int Open, 2017
Veldhuijzen G   +5 more
europepmc   +1 more source

Structuring Services and Facilities for Library Instruction [PDF]

open access: yes, 1980
published or submitted for ...
Kennedy, James R., Jr.   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy