Results 61 to 70 of about 286,457 (305)

The Iterative Development of the Humanoid Robot Kaspar: An Assistive Robot for Children with Autism [PDF]

, 2017
This paper gives an overview of the design and development of the humanoid robot Kaspar. Since the first Kaspar robot was developed in 2005, the robotic platform has undergone continuous development driven by the needs of users and technological ...
Dautenhahn, Kerstin, Novanda, Ori, Robins, Ben, Walters, Michael, Wood, Luke, Zaraki, Abolfazl   +5 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Effect of Computer-Assisted Cognitive Remediation Therapy on Cognitive Function, Social Function and Quality of Life in Patients with Vascular Dementia

Journal of Multidisciplinary Healthcare, 2022
Hai-Ying Chen,1,* Ming-Chao Li,2,* Dan Liao,1 Chi Li,1 Qiu-Ming Ji,1 Ping Guo,1 Zou Su,1 Yu-Hong Yang,1 Wen-Hao Xiao,1 Wen-Hui Zhai1 1Department of Psychiatry, Wuhan Wudong Hospital, Wuhan, People’s Republic of China; 2Department of Psychiatry ...
Chen HY, Li MC, Liao D, Li C, Ji QM, Guo P, Su Z, Yang YH, Xiao WH, Zhai WH   +9 more
doaj  

Designing an automated clinical decision support system to match clinical practice guidelines for opioid therapy for chronic pain [PDF]

, 2010
Background Opioid prescribing for chronic pain is common and controversial, but recommended clinical practices are followed inconsistently in many clinical settings.
AP Farmer, AX Garg, BM Kuehn, Brigit Vucic, Charles D Sintek, Dan Wang, David J Clark, Denise Daniels, DF Sittig, DL Hunt, DW Bates, G Worrall, J Gennari, Jack Rosenberg, Jan Elliott, JC Ballantyne, Jodie A Trafton, K Kawamoto, K Redmond, L Manchikanti, LM Frantsve, LM Yanni, M Glajchen, M Goldstein, Martha C Michel, Mary K Goldstein, MC Michel, Michael E Clark, MJ Pletcher, MK Goldstein, MK Goldstein, MK Goldstein, RA Miller, RN Shiffman, S Martins, Samson W Tu, SM Maviglia, SR Savage, Steve Balt, Susana B Martins, SW Tu, SW Tu, VA/DoD Opioid Therapy for Chronic Pain Working Group, W Dick, WM Tierney   +44 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Design and evaluation of a motor imagery electroencephalogram-controlled robot system

Advances in Mechanical Engineering, 2015
Brain–computer interface provides a new communication channel to control external device by directly translating the brain activity into commands. In this article, as the foundation of electroencephalogram-based robot-assisted upper limb rehabilitation ...
Baoguo Xu, Aiguo Song, Guopu Zhao, Guozheng Xu, Lizheng Pan, Renhuan Yang, Huijun Li, Jianwei Cui   +7 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

A perspective on the control of FES-supported standing [PDF]

, 1998
This special section is about the control of electrical stimulators to restore standing functions to paraplegics. It addresses several important topics regarding the interactions of the intact central nervous systems (CNS) with the artificial control ...
Donaldson, Nick, Veltink, Peter H.
core   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source