Results 31 to 40 of about 1,382,460 (333)

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

Subjective Quality Assessment for Images Generated by Computer Graphics

open access: yes2022 IEEE 24th International Workshop on Multimedia Signal Processing (MMSP), 2022
With the development of rendering techniques, computer graphics generated images (CGIs) have been widely used in practical application scenarios such as architecture design, video games, simulators, movies, etc. Different from natural scene images (NSIs), the distortions of CGIs are usually caused by poor rending settings and limited computation ...
Wang, Tao   +5 more
openaire   +2 more sources

Tangent Images for Mitigating Spherical Distortion [PDF]

open access: yesComputer Vision and Pattern Recognition, 2019
In this work, we propose "tangent images," a spherical image representation that facilitates transferable and scalable 360 degree computer vision. Inspired by techniques in cartography and computer graphics, we render a spherical image to a set of ...
Marc Eder   +3 more
semanticscholar   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Imaginary spaces [PDF]

open access: yes, 2007
Current three dimensional computer graphics technology has given artists and computer generated images. Imaginary Spaces is a series of images which visually depict two unique and imaginative digitally produced environments.
Weisbard, Daniel J.
core   +1 more source

VectorTalker: SVG Talking Face Generation with Progressive Vectorisation [PDF]

open access: yesarXiv, 2023
High-fidelity and efficient audio-driven talking head generation has been a key research topic in computer graphics and computer vision. In this work, we study vector image based audio-driven talking head generation. Compared with directly animating the raster image that most widely used in existing works, vector image enjoys its excellent scalability ...
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Im2Vec: Synthesizing Vector Graphics without Vector Supervision [PDF]

open access: yesarXiv, 2021
Vector graphics are widely used to represent fonts, logos, digital artworks, and graphic designs. But, while a vast body of work has focused on generative algorithms for raster images, only a handful of options exists for vector graphics. One can always rasterize the input graphic and resort to image-based generative approaches, but this negates the ...
arxiv  

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