Results 41 to 50 of about 2,686,100 (299)

Device for handling printed circuit cards Patent [PDF]

open access: yes, 1971
Handling tool for printed circuit ...
West, R. L.
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Kompetensi pembimbing syarikat bertauliah Sistem Latihan Dual Nasional (SLDN) [PDF]

open access: yes, 2015
Sistem Latihan Dual Nasional (SLDN) merupakan satu sistem latihan dan usahasama antara sektor awam dan sektor swasta dilaksanakan untuk melahirkan tenaga mahir k-worker selari dengan keperluan industri masa kini untuk membangunkan ekonomi negara.
Md.Jizat, Nor Atikah
core   +1 more source

What is usability in the context of the digital library and how can it be measured? [PDF]

open access: yes, 2005
This paper reviews how usability has been defined in the context of the digital library, what methods have been applied and their applicability, and proposes an evaluation model and a suite of instruments for evaluating usability for academic digital ...
Jeng, Judy
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Wave Transmision on Interlocking Concrete Block Submerged Breakwater

open access: yesJurnal Teknik Hidraulik, 2018
When a large dimension of rock needed for an armored layer of breakwater, the scarcity of it became a major adversity, because of that many research subject of using concrete as a substitute for rock performed.
I Ketut Dharma Setiawan
doaj   +1 more source

When Theory Meets Methods: The Naissance of Computer Assisted Corporate Interlock Research [PDF]

open access: yesSSRN Electronic Journal, 2017
AbstractIn this article, we study the emergence of computer aided network analysis as an example of ‘Mertonian’ multiple discovery. Computer assisted quantitative network analysis emerged around 1970 and small groups of researchers in different universities, who were independent of each other and looking for the right concepts and computer programs to ...
Fennema, M., Heemskerk, E.M.
openaire   +3 more sources

Design and analysis of a wire-driven flexible manipulator for bronchoscopic interventions [PDF]

open access: yes, 2016
Bronchoscopic interventions are widely performed for the diagnosis and treatment of lung diseases. However, for most endobronchial devices, the lack of a bendable tip restricts their access ability to get into distal bronchi with complex bifurcations ...
Bergeles, C, Liu, N, Yang, G-Z
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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