Results 171 to 180 of about 1,880,786 (300)

Why Is Only Type 1 Electrocardiogram Diagnostic of Brugada Syndrome? Mechanistic Insights From Computer Modeling. [PDF]

Circ Arrhythm Electrophysiol, 2022
Zhang Z, Chen PS, Weiss JN, Qu Z.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Using computer modeling to find new LRRK2 inhibitors for parkinson's disease. [PDF]

Sci Rep
García MC, Cuesta SA, Mora JR, Paz JL, Marrero-Ponce Y, Alexis F, Márquez EA.   +6 more
europepmc   +1 more source

CORR Insights®: A Simple Method to Improve Detection of Femoral Nail Abutment in the Distal Femur: A Computer Modeling Study. [PDF]

Clin Orthop Relat Res, 2022
DeCoster TA.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Comparison of efficiency of PFA catheter designs by computer modeling. [PDF]

J Cardiovasc Electrophysiol
Belalcazar A, Heist EK.
europepmc   +1 more source

Computer Modeling Explains the Structural Reasons for the Difference in Reactivity of Amine Transaminases Regarding Prochiral Methylketones. [PDF]

Int J Mol Sci, 2022
Teixeira IS, Farias AB, Horta BAC, Milagre HMS, de Souza ROMA, Bornscheuer UT, Milagre CDF.   +6 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Concurrent Micra Leadless Pacemaker Implantation and AVN Ablation: Computer Modeling of Novel Risk Mitigation Strategy. [PDF]

Pacing Clin Electrophysiol
Nelson DW, Erickson L, Zilinski JL, Zhao Y, Karos A, Whitman T, Niazi IK.   +6 more
europepmc   +1 more source

Endoscopic Paramaxillary Approach to the Infratemporal Fossa and Pterygomaxillary Space: Computer Modeling Analysis and Clinical Series. [PDF]

J Neurol Surg B Skull Base, 2022
Konuthula N, Abuzeid WM, Humphreys IM, Bly RA, Moe K.   +4 more
europepmc   +1 more source