Large-scale analysis and computer modeling reveal hidden regularities behind variability of cell division patterns in <i>Arabidopsis thaliana</i> embryogenesis. [PDF]
Laruelle E +4 more
europepmc +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Comparison of efficiency of PFA catheter designs by computer modeling. [PDF]
Belalcazar A, Heist EK.
europepmc +1 more source
Computer Modeling Explains the Structural Reasons for the Difference in Reactivity of Amine Transaminases Regarding Prochiral Methylketones. [PDF]
Teixeira IS +6 more
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Concurrent Micra Leadless Pacemaker Implantation and AVN Ablation: Computer Modeling of Novel Risk Mitigation Strategy. [PDF]
Nelson DW +6 more
europepmc +1 more source
Computer Modeling of Clot Retrieval-Circle of Willis. [PDF]
Phan TG +6 more
europepmc +1 more source
Visualizing and Modeling Categorical Time Series Data
Categorical time series data can not be effectively visualized and modeled using methods developed for ordinary data. The arbitrary mapping of categorical data to ordinal values can have a number of undesirable consequences.
Ribler, Randy +2 more
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Symposium proposal computer-based modeling in science: the case of stagecast creator
Περιέχει τη περίληψηThere is a longstanding awareness of the need to help students learn about models and modeling in science, and computer-based programming environments are promising tools for this.
Constantinou, Constantinos P. +4 more
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