A Simple Method to Improve Detection of Femoral Nail Abutment in the Distal Femur: A Computer Modeling Study. [PDF]
Clin Orthop Relat Res, 2022 Sarai H, Schmutz B, Schuetz M.
europepmc +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Computer modeling of spatial dynamics and primary genetic divergence for a population system in a ring areal. [PDF]
Vavilovskii Zhurnal Genet SelektsiiKulakov MP, Zhdanova OL, Frisman EY.
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Why Is Only Type 1 Electrocardiogram Diagnostic of Brugada Syndrome? Mechanistic Insights From Computer Modeling. [PDF]
Circ Arrhythm Electrophysiol, 2022 Zhang Z, Chen PS, Weiss JN, Qu Z.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Using computer modeling to find new LRRK2 inhibitors for parkinson's disease. [PDF]
Sci RepGarcía MC +6 more
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CORR Insights®: A Simple Method to Improve Detection of Femoral Nail Abutment in the Distal Femur: A Computer Modeling Study. [PDF]
Clin Orthop Relat Res, 2022 DeCoster TA.
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Comparison of efficiency of PFA catheter designs by computer modeling. [PDF]
J Cardiovasc ElectrophysiolBelalcazar A, Heist EK.
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Endoscopic Paramaxillary Approach to the Infratemporal Fossa and Pterygomaxillary Space: Computer Modeling Analysis and Clinical Series. [PDF]
J Neurol Surg B Skull Base, 2022 Konuthula N +4 more
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