Results 101 to 110 of about 2,661,670 (316)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

The arpanet and computer networks [PDF]

open access: yesProceedings of the ACM Conference on The history of personal workstations, 1986
In 1964 only large mainframe computers existed, each with its own separate set of users. If you were lucky the computer was timeshared, but even then you could not go far away since the terminals were hardwired to it or connected by local phone line. Moreover, if you wanted data from another computer you moved it by tape and you could forget wanting ...
openaire   +3 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Large scale network worm detection using automatic signature extraction

open access: yesTongxin xuebao, 2006
Worms had done serious harm to the computer networks due to their propagating speeds.The research was necessary to detect worms quickly and automatically.In large scale networks,flux based anomaly found module was used to screen out anomalous network ...
WANG Ping, FANG Bin-xing, YUN Xiao-chun
doaj  

Computer-based communication in support of scientific and technical work [PDF]

open access: yes
Results are reported of the first experiments for a computer conference management information system at the National Aeronautics and Space Administration.
Vallee, J., Wilson, T.
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Networking for Computer Games [PDF]

open access: yesInternational Journal of Computer Games Technology, 2008
Networking has become the main selling point for computer games: commercial games are expected to support multiplaying and the online game sites aim at supporting an ever increasing number of users. At the same time, new game console releases rely heavily on the appeal of online gaming, and a whole new branch of mobile entertainment has emerged with ...
openaire   +3 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

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