Results 61 to 70 of about 1,267,704 (337)

AppSlice: A system for application-centric design of 5G and edge computing applications [PDF]

arXiv, 2021
Applications that use edge computing and 5G to improve response times consume both compute and network resources. However, 5G networks manage only network resources without considering the application's compute requirements, and container orchestration frameworks manage only compute resources without considering the application's network requirements ...
arxiv  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Overcoming Illegal Cross-border Transfer of Personal Data

Journal of Digital Technologies and Law
Objective: to form of a comprehensive interdisciplinary legal and technological risk management model in the field of illegal cross-border transfer of personal data by eliminating legislative gaps and creating a system for automated control of outgoing ...
D. V. Bakhteev, A. M. Sosnovikova, E. V. Kazenas   +2 more
doaj   +1 more source

RELIABILITY ANALYSIS OF COMPUTER NETWORKS USING PARAMETRIC FAILURE CRITERIA

Статистика и экономика, 2016
A mathematical model, which allows to obtain expressions for the determination of parameters of reliability of computer ne t w o rks co n sis t i n g o f i den t i c al recoverable elements.
Oleg A. Tkachev
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

A Metadata Registry for Metadata Interoperability

Data Science Journal, 2007
In order to use distributed and heterogeneous scientific databases effectively, semantic heterogeneities have to be detected and resolved. To solve this problem, we propose architecture for managing metadata and metadata schema using a metadata registry.
Jian-hui Li, Jia-xin Gao, Ji-nong Dong, Wei Wu, Yan-fei Hou   +4 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Computer Network System for Fire Flame detection from Digital Video using Fractal Geometry [PDF]

Al-Rafidain Journal of Computer Sciences and Mathematics, 2010
This research aims to build a computer network system that works on detecting and locating flame by using fractal geometry in the digital video through building the network system in a server-client structure through which the characteristics of both the
Laheeb Ibrahim, Khalil Alsaif, Hasan Ahmed   +2 more
doaj   +1 more source